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- Title
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway.
- Authors
Yano, Shigetoshi; Tokumitsu, Hiroshi
- Abstract
Reports that calcium/calmodulin-dependent protein kinase (CAM-KK) activates protein kinase B (PKB) directly. How CAM-KK activates PKB in cells; Increase in apoptosis due to serum withdrawal; Significance of programmed neuronal cell death in vertebrate neural development.
- Subjects
CALCIUM; PROTEIN kinases; PHOSPHORYLATION; BIOCHEMICAL mechanism of action
- Publication
Nature, 1998, Vol 396, Issue 6711, p584
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/25147