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- Title
Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice.
- Authors
Mulle, Christophe; Sailer, Andreas; Pérez-Otaño, Isabel; Dickson-Anson, Heather; Castillo, Pablo E.; Bureau, Ingrid; Maron, Cornelia; Gage, Fred H.; Mann, Jeffrey R.; Bettler, Bernhard; Heinemann, Stephen F.
- Abstract
Presents research which generated mutant mice lacking the kainate-receptor subunit GluR6. Interaction of L-glutamate on ionotropic receptors; Similarity between kainate and AMPA receptors; Traits of mutant mice; C3 neurons in such mice; Role of kainate receptors with GluR6 subunit in synaptic transmission and the epileptogenic effects of kainate.
- Subjects
NEUROTRANSMITTER receptors; NEURAL transmission; CELL receptors
- Publication
Nature, 1998, Vol 392, Issue 6676, p601
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/33408