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- Title
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.
- Authors
Boehm, Thomas; Folkman, Judah
- Abstract
Presents research which studied the effects of the angiogenesis inhibitor endostatin on mice bearing Lewis lung carcinoma. Problem of acquired drug resistance; Cause of resistance; Stability of endothelial cells; Methods of study; Result of no development of drug resistance; Unexpected findings.
- Subjects
DRUG resistance in cancer cells; NEOVASCULARIZATION inhibitors; TUMORS; DRUG therapy
- Publication
Nature, 1997, Vol 390, Issue 6658, p404
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/37126