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- Title
SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo.
- Authors
Fukuda, Hiroshi; Seyama, Kuniaki; Ito, Kanami; Ai, Tomohiko; Nojiri, Shuko; Hori, Satoshi; Wakita, Mitsuru; Saito, Kaori; Shida, Yuka; Nagura, Rie; Hasegawa, Mayu; Kanemoto, Chiaki; Tokuhara, Mayumi; Okajima, Katsunobu; Yoshikawa, Yukio; Katsuta, Narimasa; Yamamoto, Takamasa; Idei, Mayumi; Horiuchi, Yuki; Yamatani, Kotoko
- Abstract
Healthcare workers (HCWs) are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The actual coronavirus disease (COVID-19) situation, especially in regions that are less affected, has not yet been determined. This study aimed to assess the seroprevalence of SARS-CoV-2 in HCWs working in a frontline hospital in Tokyo, Japan. In this cross-sectional observational study, screening was performed on consented HCWs, including medical, nursing, and other workers, as part of a mandatory health checkup. The screening test results and clinical characteristics of the participants were recorded. The antibody seroprevalence rate among the 4147 participants screened between July 6 and August 21, 2020, was 0.34% (14/4147). There was no significant difference in the seroprevalence rate between frontline HCWs with a high exposure risk and HCWs working in other settings with a low exposure risk. Of those seropositive for SARS-CoV-2, 64% (9/14) were not aware of any symptoms and had not previously been diagnosed with COVID-19. In conclusion, this study provides insights into the extent of infection and immune status in HCWs in Japan, which has a relatively low prevalence of COVID-19. Our findings aid in formulating public health policies to control virus spread in regions with low-intensity COVID-19.
- Subjects
TOKYO (Japan); SEROPREVALENCE; SARS-CoV-2; HOSPITAL medical staff; CROSS-sectional method; PUBLIC health laws
- Publication
Scientific Reports, 2021, Vol 11, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-021-87688-9