We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Transoral robotic surgery for oropharyngeal carcinoma: Surgical margins and oncologic outcomes.
- Authors
Moore, Eric J.; Van Abel, Kathryn M.; Price, Daniel L.; Lohse, Christine M.; Olsen, Kerry D.; Jackson, Ryan S.; Martin, Eliot J.
- Abstract
Abstract: Background: This study presents oncologic outcomes after transoral robotic surgery (TORS) ± adjuvant therapy for oropharyngeal squamous cell carcinoma (SCC). Methods: Three hundred fourteen patients undergoing TORS ± adjuvant therapy for oropharyngeal SCC from May 1, 2007, to May 31, 2015, are analyzed. Results: Median follow‐up was 3.3 years (interquartile range [IQR] 1.8‐5.3 years; range 1 day to 9.3 years). Estimated locoregional recurrence‐free survival, distant metastasis‐free survival (DMFS), overall survival (OS), and cancer‐specific survival (CSS) rates (95% confidence interval [CI] number still at risk) at 5 years after surgery were 92% (88‐95; 92), 90% (86‐94; 92), 86% (82‐92; 98), and 94% (91‐97; 98), respectively. Negative margins were achieved in 98% of cases. The adult comorbidity evaluation (ACE)‐27 comorbidity index, human papillomavirus (HPV) status, pathologic N classification, and number of attempts to clear margins were associated with death due to cancer (<italic>P</italic> = .003, <italic>P</italic> = .002, <italic>P</italic> = .030, and <italic>P</italic> = .002, respectively). Conclusion: The need to take ≥2 margins to achieve resection portends an increased risk of locoregional recurrence and death due to disease in oropharyngeal SCC.
- Subjects
LEIOMYOSARCOMA; TUMORS; ONCOLOGY; CANCER; METASTASIS
- Publication
Head & Neck, 2018, Vol 40, Issue 4, p747
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.25055