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- Title
Bubble CPAP versus Ventilator CPAP in Preterm Neonates with Early Onset Respiratory Distress—A Randomized Controlled Trial.
- Authors
Tagare, Amit; Kadam, Sandeep; Vaidya, Umesh; Pandit, Anand; Patole, Sanjay
- Abstract
Bubble continuous positive airway pressure (BCPAP) is a low cost nasal CPAP delivery system with potential benefits to developing nations.Objective: To compare the efficacy and safety of BCPAP with ventilator-derived CPAP (VCPAP) in preterm neonates with respiratory distress.Methods: In a randomized controlled trial, preterm neonates with Silverman–Anderson score &geq;4 and oxygen requirement >30% within first 6 h of life were randomly allocated to BCPAP or VCPAP. Proportion of neonates with success or failure was compared.Results: In all, 47 of 57 (82.5%) neonates from BCPAP group and 36 of 57 (63.2%) neonates from the VCPAP group completed CPAP successfully (p = 0.03). Neonates who failed CPAP had higher Silverman–Anderson score (p < 0.01), lower arterial to alveolar oxygenation ratio (p < 0.05) and needed surfactant more frequently (p < 0.01).Conclusion: BCPAP has higher success rate than VCPAP for managing preterm neonates with early onset respiratory distress, with comparable safety.
- Subjects
CONTINUOUS positive airway pressure; MECHANICAL ventilators; PREMATURE infants; RESPIRATORY distress syndrome; RANDOMIZED controlled trials; MEDICAL care costs; COMPARATIVE studies
- Publication
Journal of Tropical Pediatrics, 2013, Vol 59, Issue 2, p113
- ISSN
0142-6338
- Publication type
Article
- DOI
10.1093/tropej/fms061