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Structural and sequencing analysis of local target DNA recognition by MLV integrase.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 11, p. 5647, doi. 10.1093/nar/gkv410
By:
- Aiyer, Sriram;
- Rossi, Paolo;
- Malani, Nirav;
- Schneider, William M.;
- Chandar, Ashwin;
- Bushman, Frederic D.;
- Montelione, Gaetano T.;
- Roth, Monica J.
Publication type:
Article
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 9, p. 5917, doi. 10.1093/nar/gku175
By:
- Aiyer, Sriram;
- Swapna, G. V. T.;
- Malani, Nirav;
- Aramini, James M.;
- Schneider, William M.;
- Plumb, Matthew R.;
- Ghanem, Mustafa;
- Larue, Ross C.;
- Sharma, Amit;
- Studamire, Barbara;
- Kvaratskhelia, Mamuka;
- Bushman, Frederic D.;
- Montelione, Gaetano T.;
- Roth, Monica J.
Publication type:
Article
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 9, p. 5917, doi. 10.1093/nar/gku175
By:
- Aiyer, Sriram;
- Swapna, G.V.T.;
- Malani, Nirav;
- Aramini, James M.;
- Schneider, William M.;
- Plumb, Matthew R.;
- Ghanem, Mustafa;
- Larue, Ross C.;
- Sharma, Amit;
- Studamire, Barbara;
- Kvaratskhelia, Mamuka;
- Bushman, Frederic D.;
- Montelione, Gaetano T.;
- Roth, Monica J.
Publication type:
Article
Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 8, p. 4868, doi. 10.1093/nar/gku135
By:
- Larue, Ross C.;
- Plumb, Matthew R.;
- Crowe, Brandon L.;
- Shkriabai, Nikoloz;
- Sharma, Amit;
- DiFiore, Julia;
- Malani, Nirav;
- Aiyer, Sriram S.;
- Roth, Monica J.;
- Bushman, Frederic D.;
- Foster, Mark P.;
- Kvaratskhelia, Mamuka
Publication type:
Article
A method to sequence and quantify DNA integration for monitoring outcome in gene therapy.
Published in:
Nucleic Acids Research, 2011, v. 39, n. 11, p. e72, doi. 10.1093/nar/gkr140
By:
- Brady, Troy;
- Roth, Shoshannah L.;
- Malani, Nirav;
- Wang, Gary P.;
- Berry, Charles C.;
- Leboulch, Philippe;
- Hacein-Bey-Abina, Salima;
- Cavazzana-Calvo, Marina;
- Papapetrou, Eirini P.;
- Sadelain, Michel;
- Savilahti, Harri;
- Bushman, Frederic D.
Publication type:
Article
Bacteriophage Mu integration in yeast and mammalian genomes.
Published in:
Nucleic Acids Research, 2008, v. 36, n. 22, p. e148, doi. 10.1093/nar/gkn801
By:
- Paatero, Anja O.;
- Turakainen, Hilkka;
- Happonen, Lotta J.;
- Olsson, Cia;
- Palomäki, Tiina;
- Pajunen, Maria I.;
- Meng, Xiaojuan;
- Otonkoski, Timo;
- Tuuri, Timo;
- Berry, Charles;
- Malani, Nirav;
- Frilander, Mikko J.;
- Bushman, Frederic D.;
- Savilahti, Harri
Publication type:
Article
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells.
Published in:
Nature Biotechnology, 2011, v. 29, n. 1, p. 73, doi. 10.1038/nbt.1717
By:
- Papapetrou, Eirini P.;
- Lee, Gabsang;
- Malani, Nirav;
- Setty, Manu;
- Riviere, Isabelle;
- Tirunagari, Laxmi M. S.;
- Kadota, Kyuichi;
- Roth, Shoshannah L.;
- Giardina, Patricia;
- Viale, Agnes;
- Leslie, Christina;
- Bushman, Frederic D.;
- Studer, Lorenz;
- Sadelain, Michel
Publication type:
Article
Comparative Analysis of the Recently Discovered hAT Transposon TcBuster in Human Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0042666
By:
- Woodard, Lauren E.;
- Xianghong Li;
- Malani, Nirav;
- Kaja, Aparna;
- Hice, Robert H.;
- Atkinson, Peter W.;
- Bushman, Frederic D.;
- Craig, Nancy L.;
- Wilson, Matthew H.
Publication type:
Article
High-Definition Mapping of Retroviral Integration Sites Defines the Fate of Allogeneic T Cells After Donor Lymphocyte Infusion.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015688
By:
- Cattoglio, Claudia;
- Maruggi, Giulietta;
- Bartholomae, Cynthia;
- Malani, Nirav;
- Pellin, Danilo;
- Cocchiarella, Fabienne;
- Magnani, Zulma;
- Ciceri, Fabio;
- Ambrosi, Alessandro;
- von Kalle, Christof;
- Bushman, Frederic D.;
- Bonini, Chiara;
- Schmidt, Manfred;
- Mavilio, Fulvio;
- Recchia, Alessandra
Publication type:
Article
In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Published in:
Nature, 2011, v. 475, n. 7355, p. 217, doi. 10.1038/nature10177
By:
- Hojun Li;
- Haurigot, Virginia;
- Doyon, Yannick;
- Tianjian Li;
- Wong, Sunnie Y.;
- Bhagwat, Anand S.;
- Malani, Nirav;
- Anguela, Xavier M.;
- Sharma, Rajiv;
- Ivanciu, Lacramiora;
- Murphy, Samuel L.;
- Finn, Jonathan D.;
- Khazi, Fayaz R.;
- Shangzhen Zhou;
- Paschon, David E.;
- Rebar, Edward J.;
- Bushman, Frederic D.;
- Gregory, Philip D.;
- Holmes, Michael C.;
- High, Katherine A.
Publication type:
Article
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors.
Published in:
Molecular Diagnosis & Therapy, 2023, v. 27, n. 6, p. 753, doi. 10.1007/s40291-023-00670-1
By:
- Zhao, Jianhua;
- Reuther, Jacquelyn;
- Scozzaro, Kaylee;
- Hawley, Megan;
- Metzger, Emily;
- Emery, Matthew;
- Chen, Ingrid;
- Barbosa, Michelle;
- Johnson, Laura;
- O'Connor, Alijah;
- Washburn, Mike;
- Hartje, Luke;
- Reckase, Erik;
- Johnson, Verity;
- Zhang, Yuhua;
- Westheimer, Emily;
- O'Callaghan, William;
- Malani, Nirav;
- Chesh, Adrian;
- Moreau, Michael
Publication type:
Article
A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Published in:
PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004171
By:
- Sharma, Amit;
- Slaughter, Alison;
- Jena, Nivedita;
- Feng, Lei;
- Kessl, Jacques J.;
- Fadel, Hind J.;
- Malani, Nirav;
- Male, Frances;
- Wu, Li;
- Poeschla, Eric;
- Bushman, Frederic D.;
- Fuchs, James R.;
- Kvaratskhelia, Mamuka
Publication type:
Article
The Major Cellular Sterol Regulatory Pathway Is Required for Andes Virus Infection.
Published in:
PLoS Pathogens, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.ppat.1003911
By:
- Petersen, Josiah;
- Drake, Mary Jane;
- Bruce, Emily A.;
- Riblett, Amber M.;
- Didigu, Chukwuka A.;
- Wilen, Craig B.;
- Malani, Nirav;
- Male, Frances;
- Lee, Fang-Hua;
- Bushman, Frederic D.;
- Cherry, Sara;
- Doms, Robert W.;
- Bates, Paul;
- Briley Jr., Kenneth
Publication type:
Article
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2.
Published in:
PLoS Pathogens, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.ppat.1001313
By:
- Ocwieja, Karen E.;
- Brady, Troy L.;
- Ronen, Keshet;
- Huegel, Alyssa;
- Roth, Shoshannah L.;
- Schaller, Torsten;
- James, Leo C.;
- Towers, Greg J.;
- Young, John A. T.;
- Chanda, Sumit K.;
- nig, Renate Kö;
- Malani, Nirav;
- Berry, Charles C.;
- Bushman, Frederic D.
Publication type:
Article
Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies.
Published in:
PLoS Pathogens, 2009, v. 5, n. 5, p. 1, doi. 10.1371/journal.ppat.1000437
By:
- Bushman, Frederic D.;
- Malani, Nirav;
- Fernandes, Jason;
- D'Orso, Iván;
- Cagney, Gerard;
- Diamond, Tracy L.;
- Honglin Zhou;
- Hazuda, Daria J.;
- Espeseth, Amy S.;
- König, Renate;
- Bandyopadhyay, Sourav;
- Ideker, Trey;
- Goff, Stephen P.;
- Krogan, Nevan J.;
- Frankel, Alan D.;
- Young, John A. T.;
- Chanda, Sumit K.
Publication type:
Article
Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia.
Published in:
Molecular Therapy, 2011, v. 19, n. 7, p. 1273, doi. 10.1038/mt.2011.20
By:
- Ronen, Keshet;
- Negre, Olivier;
- Roth, Shannah;
- Colomb, Charlotte;
- Malani, Nirav;
- Denaro, Maria;
- Brady, Troy;
- Fusil, Floriane;
- Gillet-Legrand, Beatrix;
- Hehir, Kathleen;
- Beuzard, Yves;
- Leboulch, Philippe;
- Down, Julian D.;
- Payen, Emmanue.l;
- Bushman, Frederic D
Publication type:
Article
LEDGF Hybrids Efficiently Retarget Lentiviral Integration Into Heterochromatin.
Published in:
Molecular Therapy, 2010, v. 18, n. 3, p. 552, doi. 10.1038/mt.2010.36
By:
- Gijsbers, Rik;
- Ronen, Keshet;
- Vets, Sofie;
- Malani, Nirav;
- De Rijck, Jan;
- McNeely, Melissa;
- Bushman, Frederic D.;
- Debyser, Zeger
Publication type:
Article
Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells.
Published in:
Molecular Therapy, 2009, v. 17, n. 5, p. 844, doi. 10.1038/mt.2009.16
By:
- Wang, Gary P.;
- Levine, Bruce L.;
- Binder, Gwendolyn K.;
- Berry, Charles C.;
- Malani, Nirav;
- McGarrity, Gary;
- Tebas, Pablo;
- June, Carl H.;
- Bushman, Frederic D.
Publication type:
Article
Comparing DNA integration site clusters with scan statistics.
Published in:
Bioinformatics, 2014, v. 30, n. 11, p. 1493, doi. 10.1093/bioinformatics/btu035
By:
- Berry, Charles C.;
- Ocwieja, Karen E.;
- Malani, Nirav;
- Bushman, Frederic D.
Publication type:
Article
BET proteins target murine leukemia virus integration to transcription start sites.
Published in:
2013
By:
- Sharma, Amit;
- Larue, Ross;
- Plumb, Matthew;
- Malani, Nirav;
- Male, Frances;
- Slaughter, Alison;
- Kessl, Jacques;
- Shkriabai, Nikoloz;
- Coward, Elizabeth;
- Aiyer, Sriram;
- Green, Patrick;
- Li Wu;
- Roth, Monica;
- Bushman, Frederic;
- Kvaratskhelia, Mamuka
Publication type:
Abstract
Bromodomain and extra-terminal (BET) proteins target Moloney murine leukemia virus integration to transcription start sites.
Published in:
2013
By:
- De Riick, Jan;
- De Kogel, Christine;
- Demeulemeester, Jonas;
- Vets, Sofie;
- Malani, Nirav;
- Bushman, Frederic D.;
- Busschots, Katrien;
- Husson, Steven;
- Gijsbers, Rik;
- Debyser, Zeger
Publication type:
Abstract
HIV latency and integration site placement in five cell-based models.
Published in:
Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-90
By:
- Sherrill-Mix, Scott;
- Lewinski, Mary K;
- Famiglietti, Marylinda;
- Bosque, Alberto;
- Malani, Nirav;
- Ocwieja, Karen E;
- Berry, Charles C;
- Looney, David;
- Shan, Liang;
- Agosto, Luis M;
- Pace, Matthew J;
- Siliciano, Robert F;
- O'Doherty, Una;
- Guatelli, John;
- Planelles, Vicente;
- Bushman, Frederic D
Publication type:
Article
HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.
Published in:
Retrovirology, 2012, v. 9, n. 1, p. 84, doi. 10.1186/1742-4690-9-84
By:
- Schrijvers, Rik;
- Vets, Sofie;
- De Rijck, Jan;
- Malani, Nirav;
- Bushman, Frederic D.;
- Debyser, Zeger;
- Gijsbers, Rik
Publication type:
Article
HTLV-1 clonality during chronic infection and BLV clonality during primary infection.
Published in:
2011
By:
- Gillet, Nicolas A.;
- Hlela, Carol;
- Verdonck, Tine;
- Gotuzzo, Eduardo;
- Clark, Daniel;
- Rodriguez, Sabrina;
- Malani, Nirav;
- Melamed, Anat;
- Gormley, Niall;
- Carter, Richard;
- Bentley, David;
- Berry, Charles;
- Bushman, Frederic D.;
- Taylor, Graham P.;
- Willems, Luc;
- Bangham, Charles R. M.
Publication type:
Abstract

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