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- Title
Haeme oxygenase promotes progenitor cell mobilization, neovascularization, and functional recovery after critical hindlimb ischaemia in mice.
- Authors
Tongers, Jörn; Knapp, Julia-Marie; Korf, Mortimer; Kempf, Tibor; Limbourg, Anne; Limbourg, Florian P.; Zhixiong Li; Fraccarollo, Daniela; Bauersachs, Johann; Han, Xiaoqiang; Drexler, Helmut; Fiedler, Beate; Wollert, Kai C.
- Abstract
Aims: Neovascularization is an important element of long-term functional recovery during chronic ischaemia. We postulated that haeme oxygenase (HO) is required for progenitor cell recruitment, neovascularization, and blood flow recovery after critical hindlimb ischaemia (HLI).
- Subjects
HEME oxygenase; CELL motility; NEOVASCULARIZATION; HINDLIMB; ISCHEMIA; MOUSE diseases
- Publication
Cardiovascular Research, 2008, Vol 78, Issue 2, p294
- ISSN
0008-6363
- Publication type
Article
- DOI
10.1093/cvr/cvm107