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- Title
Women's attitude towards routine human platelet antigen-screening in pregnancy.
- Authors
Winkelhorst, Dian; Loeff, Rosanne M.; Akker‐Van Marle, M. Elske; Haas, Masja; Oepkes, Dick; van den Akker-Van Marle, M Elske; de Haas, Masja
- Abstract
<bold>Introduction: </bold>Fetal and neonatal alloimmune thrombocytopenia is a potentially life-threatening disease with excellent preventative treatment available for subsequent pregnancies. To prevent index cases, the effectiveness of a population-based screening program has been suggested repeatedly. Therefore, we aimed to evaluate women's attitude towards possible future human platelet antigen-screening in pregnancy.<bold>Material and Methods: </bold>We performed a cross-sectional questionnaire study among healthy pregnant women receiving prenatal care in one of seven participating midwifery practices. Attitude was assessed using a questionnaire based on the validated Multidimensional Measurement of Informed Choice model, containing questions assessing knowledge, attitude and intention to participate.<bold>Results: </bold>A total of 143 of the 220 women (65%) completed and returned the questionnaire. A positive attitude towards human platelet antigen-screening was expressed by 91% of participants, of which 94% was based on sufficient knowledge. Attitude was more likely to be negatively influenced by the opinion that screening can be frightening. Informed choices were made in 87% and occurred significantly less in women from non-European origin, 89% in European women vs. 60% in non-European women (p = 0.03).<bold>Conclusions: </bold>Pregnant women in the Netherlands expressed a positive attitude towards human platelet antigen-screening in pregnancy. We therefore expect a high rate of informed uptake when human platelet antigen-screening is implemented. In future counseling on human platelet antigen-screening, ethnicity and possible anxiety associated with a screening test need to be specifically addressed.
- Subjects
NETHERLANDS; PREGNANT women; PREGNANCY; THROMBOCYTOPENIA; BLOOD platelets; QUESTIONNAIRES; ATTITUDE (Psychology); COMPARATIVE studies; HEALTH attitudes; ISOANTIGENS; RESEARCH methodology; MEDICAL cooperation; PRENATAL diagnosis; RESEARCH; MIDWIFERY; GENETIC testing; EVALUATION research; CROSS-sectional method; MULTIDIMENSIONAL Health Locus of Control scales; DIAGNOSIS
- Publication
Acta Obstetricia et Gynecologica Scandinavica, 2017, Vol 96, Issue 8, p991
- ISSN
0001-6349
- Publication type
journal article
- DOI
10.1111/aogs.13150