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- Title
Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association.
- Authors
Passeron, Thierry; Bahadoran, Philippe; Bertolotto, Corine; Chiaverini, Christine; Buscà, Roser; Valony, Gaëlle; Bille, Karine; Ortonne, Jean-Paul; Ballotti, Robert
- Abstract
Investigates the possible regulation of melanosome transport in mammalian melanocytes by α-melanocyte stimulating hormone. Effect of cyclic adenosine monophosphate (cAMP) activation on proteins involved in the control of melanosome transport; Role of RhoA and p160Rock in the redistribution of melanosomes; Impact of cAMP on the interaction between melanophin/Slac2-a and actin.
- Subjects
MELANOCYTES; MSH (Hormone); CYCLIC adenylic acid; PROTEINS; ACTIN
- Publication
FASEB Journal, 2004, Vol 18, Issue 9, p989
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.03-1240fje