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- Title
Total bilateral laparoscopic adrenalectomy in patients with Cushing's syndrome and multiple endocrine neoplasia (IIa).
- Authors
Fernández-Cruz, L.; Sáenz, A.; Benarroch, G.; Sabater, L.; Taurá, P.; Fernández-Cruz, L; Sáenz, A; Taurá, P
- Abstract
<bold>Background: </bold>The benefit of simultaneous bilateral laparoscopic adrenalectomy in patients with Cushing's syndrome and pheochromocytoma associated with multiple endocrine neoplasia (MEN) is unknown.<bold>Methods: </bold>Ten patients underwent laparoscopic adrenalectomy (LpA) with CO2 pneumoperitoneum for Cushing's syndrome. One MEN patient underwent simultaneous bilateral laparoscopic adrenalectomy with helium pneumoperitoneum for bilateral pheochromocytoma. A comparison was made between unilateral LpA and simultaneous bilateral laparoscopic adrenalectomy in patients with Cushing's syndrome. Plasma catecholamines were correlated with hemodynamic changes in the patient with pheochromocytoma.<bold>Results: </bold>Simultaneous bilateral laparoscopic adrenalectomy in the patient with pheochromocytoma lasted 330 min. The substantial increase in plasma catecholamines was not associated with cardiovascular instability. Operative time (270 +/- 3 vs 120 +/- 4 min), blood loss (365 +/- 1 vs 210 +/- 1 ml), hospital stay (7.6 +/- 1.5 vs 4.6 +/- 1 days), and normal activity (19.3 +/- 2 vs 10.4 +/- 4.4 days) were, in patients with Cushing's syndrome, significantly (p < 0.05) higher after simultaneous bilateral laparoscopic adrenalectomy than after unilateral LpA; the differences were not significant in the analgesic requirements (7.6 +/- 1 vs 4.6 +/- 1 doses). One patient with unilateral LpA was converted to open surgery.<bold>Conclusion: </bold>Simultaneous bilateral laparoscopic adrenalectomy is safe, and associated with short hospital stay and lessening of the time needed to achieve normal activity.
- Publication
Surgical Endoscopy, 1997, Vol 11, Issue 2, p103
- ISSN
0930-2794
- Publication type
journal article
- DOI
10.1007/s004649900307