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- Title
Fertility, Pregnancy and Delivery in Women after Biventricular Repair for Double Outlet Right Ventricle.
- Authors
Drenthen, Willem; Pieper, Petronella G.; van der Tuuk, Karin; Roos-Hesselink, Jolien W.; Hoendermis, Elke S.; Voors, Adriaan A.; Mulder, Barbara J.M.; van Dijk, Arie P.J.; Yap, Sing C.; Vliegen, Hubert W.; Moons, Philip; Ebels, Tjark; van Veldhuisen, Dirk J.
- Abstract
Objectives: To investigate outcome of pregnancy and fertility in women with double outlet right ventricle (DORV). Methods: Using 2 congenital heart disease registries, 21 female patients with DORV (aged 18–39 years) were retrospectively identified. Detailed recordings of each patient and their completed (>20 weeks gestation) pregnancies were recorded. Results: Overall, 10 patients had 19 pregnancies, including 3 spontaneous miscarriages (16%). During the 16 live birth pregnancies, primarily (serious) noncardiac complications were observed, e.g. premature labor/delivery (n = 7 and n = 3, respectively), small for gestational age (n = 4), preeclampsia (n = 2) and recurrence of congenital heart disease (n = 2). Except for postpartum endocarditis and deterioration of subpulmonary obstruction, only mild cardiac complication pregnancies were recorded. Two women with children reported secondary female infertility. Several menstrual cycle disorders were reported: secondary amenorrhea (n = 4), primary amenorrhea (n = 3) and oligomenorrhea (n = 2). Conclusion: Successful pregnancy in women with DORV is possible. Primarily noncardiac complications were observed and only few (minor) cardiac complications. Infertility and menstrual cycle disorders appear to be more prevalent. Copyright © 2007 S. Karger AG, Basel
- Subjects
HUMAN fertility; PREGNANCY; DELIVERY (Obstetrics); WOMEN'S health; RIGHT heart ventricle; CONGENITAL heart disease; ENDOCARDITIS; PREGNANCY complications; SURGERY
- Publication
Cardiology, 2008, Vol 109, Issue 2, p105
- ISSN
0008-6312
- Publication type
Article
- DOI
10.1159/000105550