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- Title
Effect of internal carotid artery stenting on mild cognitive impairment of patients with asymptomatic internal carotid artery stenosis.
- Authors
YANG Zhi-jie; GAO Zong-en; ZHANG Li-gong; CHEN Xiao-hui; LÜ Zai-gang; LI Da-wei; ZHONG Meng-fei
- Abstract
Objective To explore effect of internal carotid artery (ICA) stenting on mild cognitive impairment (MCI) of patients with asymptomatic ICA stenosis. Methods Fifty-four patients with severe ICA stenosis (stenosis rate ≥ 70%) from October 2016 to September 2018 were studied. Cognitive function was examined in 54 patients with asymptomatic ICA stenosis 24 h before operation and 1 month, 3 months, 6 months after operation. Cognitive function was assessed with the Mini-Mental State Examination (MMSE), Trail Making Test (TMT) and Stroop Color-Word Test (SCWT). Results There were statistical differences in MMSE (P = 0.000), time of TMT-A and TMT-B (P = 0.000, 0.000), time of SCWT-A, SCWT-B and SCWT- C(P = 0.000, 0.036, 0.000), and correct number of SCWT - A (P = 0.005) before and after ICA stenting. MMSE, time of TMT-A, TMT-B and SCWT-A at 3 and 6 months after stenting were shorter than before and one month after stenting (P < 0.05, for all), while time of SCWT-C was shorter than before stenting (P < 0.05, for all). Time of SCWT-B at 6 months after stenting was shorter than before stenting (P < 0.05, for all). Correct number of SCWT-A at 6 months after stenting was higher than before and 3 months after stenting (P < 0.05, for all), which at 3 monthes after stenting was lower than one month after stenting (P < 0.05, for all). Conclusions ICA stenting can help to improve the MCI patients with asymptomatic ICA stenosis.
- Subjects
CAROTID artery surgery; ANGIOPLASTY; CLINICAL trials; COGNITION disorders; NEUROPSYCHOLOGICAL tests; HEALTH outcome assessment; PSYCHOLOGICAL tests; QUESTIONNAIRES; SURGICAL stents; TIME; CAROTID artery stenosis; PRE-tests &; post-tests; DESCRIPTIVE statistics
- Publication
Chinese Journal of Contemporary Neurology & Neurosurgery, 2019, Vol 19, Issue 10, p743
- ISSN
1672-6731
- Publication type
Article
- DOI
10.3969/j.issn.1672-6731.2019.10.007