We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Ventriculoperitoneal Shunt Infections in Children: Demographical, Clinical Findings and Evaluation of Thrombocyte Parameters.
- Authors
Gündeşlioğlu, Özlem Özgür; Haytoğlu, Zeliha; Özsoy, Kerem Mazhar; Alabaz, Derya; Kocabaş, Emine
- Abstract
Objective: We investigated demographic, clinical and laboratory characteristics of children with ventriculoperitoneal (VP) shunt infection in this study. The aim of this study was to make a comparison between the values obtained before and after treatment, and those obtained before treatment and of the control groups in terms of platelet count, mean platelet volume (MPV) and platelet distribution width (PDW) values in the diagnosis of VP shunt infection. Material and Methods: In this study, medical records of patients diagnosed with VP shunt infection between the years 2015-2018 were retrospectively reviewed. Healthy children of similar age groups were selected as the control group. The platelet count, MPV and PDW values of the patients were compared before and after treatment, and before treatment and with the control group. Results:13 (39.4%) female and 20 (60.6%) male patients who were diagnosed with VP shunt infection were included in this study. The median age of the patients was 8 months (min-max: 1-106 month). The most common complaints were nausea and vomiting (66.7%) followed by loss of appetite (57.6%) and fever (51.5%). Growth in the cerebrospinal fluid (CSF) culture of 23 (69.7%) patients was detected and the most common cause was Staphylococcus epidermidis (57.6%). At admission, patients with VP shunt infection had mean follow-up platelet counts of 521.969 ± 143.697 µL (min-max: 256.000-854.000 µL) and 25 patients (75.7%) had thrombocytosis. There was statistically significant difference between before and after treatment platelet counts of the patients (p= 0.001). When MPW values were compared between before and after treatment, the mean MPW value at before treatment was 9.58 fL and the mean MPW value at after treatment was 9.87 fL, which was statistically significant (p= 0.027). The difference between PDW values before and after treatment was not statistically significant. When MPW and PDW values of the control group and the patients were compared, there was no statistical difference. Conclusion: In our study, there was no statistical difference between MPW and PDW values in healthy children and patients with VP shunt infection. However, in patients with VP shunt infection, although thrombocytosis was present at the beginning of the treatment, the values after treatment were within normal limits. At the beginning of treatment, MPW values were found to be lower than after the treatment. In the case of VP shunt infections, in order to use the platelet parameters (MPW, PDW) for diagnosis, prospective studies with more patients are needed.
- Subjects
CEREBROSPINAL fluid shunts; EATING disorders; FEVER; HOSPITAL admission &; discharge; INFECTION; PATIENTS; POSTOPERATIVE period; COMPLICATIONS of prosthesis; STAPHYLOCOCCUS; THROMBOCYTOSIS; RETROSPECTIVE studies; PREOPERATIVE period; PLATELET count; MEAN platelet volume; CHILDREN; DIAGNOSIS
- Publication
Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi, 2018, Vol 12, Issue 2, pe63
- ISSN
1307-1068
- Publication type
Article
- DOI
10.5578/ced.201812