Found: 26
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The future of drug development: advancing clinical trial design.
- Published in:
- 2009
- By:
- Publication type:
- review
Individualized treatment strategies for hyperuricemia informed by a semi-mechanistic exposure-response model of uric acid dynamics.
- Published in:
- Physiological Reports, 2018, v. 6, n. 5, p. 1, doi. 10.14814/phy2.13614
- By:
- Publication type:
- Article
Comment on the report "Limitations of model-based dose selection for indacaterol in patients with chronic obstructive pulmonary disease.".
- Published in:
- International Journal of Clinical Pharmacology & Therapeutics, 2012, v. 50, n. 9, p. 631, doi. 10.5414/CP201758A
- By:
- Publication type:
- Article
A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1997, v. 61, n. 1, p. 45, doi. 10.1016/S0009-9236(97)90181-8
- By:
- Publication type:
- Article
Population pharmacodynamic model for ketorolac analgesia<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1996, v. 60, n. 6, p. 619, doi. 10.1016/S0009-9236(96)90210-6
- By:
- Publication type:
- Article
Pharmacodynamic modeling of the electroencephalographic effects of flumazenil in healthy volunteers sedated with midazolam<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1995, v. 58, n. 5, p. 567, doi. 10.1016/0009-9236(95)90177-9
- By:
- Publication type:
- Article
Pharmacokinetic-pharmacodynamic modeling in drug development: Application to the investigational opioid trefentanil.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 3, p. 261, doi. 10.1038/clpt.1994.136
- By:
- Publication type:
- Article
Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development.
- Published in:
- Clinical Pharmacology & Therapeutics, 1992, v. 51, n. 4, p. 465, doi. 10.1038/clpt.1992.47
- By:
- Publication type:
- Article
Electroencephalographic effects of benzodiazepines. I. Choosing an electroencephalographic parameter to measure the effect of midazolam on the central nervous system.
- Published in:
- Clinical Pharmacology & Therapeutics, 1990, v. 48, n. 5, p. 544, doi. 10.1038/clpt.1990.191
- By:
- Publication type:
- Article
Electroencephalographic effects of benzodiazepines. II. Pharmacodynamic modeling of the electroencephalographic effects of midazolam and diazepam.
- Published in:
- Clinical Pharmacology & Therapeutics, 1990, v. 48, n. 5, p. 555, doi. 10.1038/clpt.1990.192
- By:
- Publication type:
- Article
Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Innovative approaches to clinical development and trial design.
- Published in:
- Annali dell'Istituto Superiore di Sanita, 2011, v. 47, n. 1, p. 8
- By:
- Publication type:
- Article
Integrating dose estimation into a decision‐making framework for model‐based drug development.
- Published in:
- Pharmaceutical Statistics, 2018, v. 17, n. 2, p. 155, doi. 10.1002/pst.1841
- By:
- Publication type:
- Article
The Titration Paradox Turns Pharmacology Upside Down.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 2, p. 292, doi. 10.1002/cpt.2235
- By:
- Publication type:
- Article
Characterization and validation of a pharmacokinetic model for controlled-release oxycodone.
- Published in:
- British Journal of Clinical Pharmacology, 1996, v. 42, n. 6, p. 747, doi. 10.1046/j.1365-2125.1996.00481.x
- By:
- Publication type:
- Article
Fostering Culture and Optimizing Organizational Structure for Implementing Model-Based Drug Development.
- Published in:
- Journal of Clinical Pharmacology, 2010, v. 50, n. 9, p. 146S, doi. 10.1177/0091270010376976
- By:
- Publication type:
- Article
Pharmacokinetic/Pharmacodynamic Modeling in Drug Research and Development.
- Published in:
- Journal of Clinical Pharmacology, 2000, v. 40, n. 12, p. 1399, doi. 10.1177/009127000004001211
- By:
- Publication type:
- Article
Opportunities for Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development.
- Published in:
- 1994
- By:
- Publication type:
- Other
Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2010, v. 37, n. 6, p. 629, doi. 10.1007/s10928-010-9184-y
- By:
- Publication type:
- Article
Exposure-Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction.
- Published in:
- Journal of Clinical Pharmacology, 2017, v. 57, n. 5, p. 573, doi. 10.1002/jcph.839
- By:
- Publication type:
- Article
Pharmacokinetics and pharmacodynamics for the clinician.
- Published in:
- Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie, 1991, v. 38, n. 1, p. R48, doi. 10.1007/BF03008434
- By:
- Publication type:
- Article
The contribution of pharmacokinetics and pharmacodynamics to clinical anaesthesia care.
- Published in:
- Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie, 1988, v. 35, n. 1, p. S42, doi. 10.1007/BF03026926
- By:
- Publication type:
- Article
Effects of cardiac surgery with cardiopulmonary bypass on lidocaine disposition.
- Published in:
- Clinical Pharmacology & Therapeutics, 1984, v. 35, n. 5, p. 617, doi. 10.1038/clpt.1984.85
- By:
- Publication type:
- Article
Haloperidol kinetics after oral and intravenous doses.
- Published in:
- Clinical Pharmacology & Therapeutics, 1983, v. 33, n. 4, p. 477, doi. 10.1038/clpt.1983.65
- By:
- Publication type:
- Article
Decreased protein binding and thiopental kinetics.
- Published in:
- Clinical Pharmacology & Therapeutics, 1982, v. 32, n. 2, p. 212, doi. 10.1038/clpt.1982.150
- By:
- Publication type:
- Article
Pyridostigmine kinetics with and without renal function.
- Published in:
- Clinical Pharmacology & Therapeutics, 1980, v. 28, n. 1, p. 78, doi. 10.1038/clpt.1980.134
- By:
- Publication type:
- Article