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- Title
Polyautoimmunity in rheumatological conditions.
- Authors
Matusiewicz, Agata; Stróżyńska‐Byrska, Joanna; Olesińska, Marzena
- Abstract
Co‐occurrence of autoimmune diseases (ADs) within an individual is postulated to be a frequent phenomenon in rheumatic diseases. Similar clinical signs and symptoms, pathophysiological mechanisms, genetic factors within autoimmune diseases and aggregation of diverse ADs within families sustain the theory of shared pathogenesis of several ADs (autoimmune tautology). Polyautoimmunity (PA) is defined as the presence of more than one autoimmune disease in a single patient. When three or more autoimmune diseases coexist, this condition is called multiple autoimmune syndrome (MAS). This analysis summarizes an estimated prevalence of PA in the most common rheumatic diseases, the presumable risk factors for PA and influence of concomitant diseases on the course of disease.
- Subjects
AUTOIMMUNE diseases; RHEUMATISM; DISEASE complications; SYMPTOMS; COMORBIDITY
- Publication
International Journal of Rheumatic Diseases, 2019, Vol 22, Issue 3, p386
- ISSN
1756-1841
- Publication type
Article
- DOI
10.1111/1756-185X.13454