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- Title
Incidence And Risk Factors For Invasive Candidiasis In A Neonatal Intensive Care Unit In Central India.
- Authors
Ansari, Iqbal Mohammed; Ahirwar, Akhilesh; Ganguly, Ananya; Jain, Samriddhi
- Abstract
Invasive candidiasis (IC) poses a significant threat to neonates in intensive care units, contributing to high morbidity and mortality rates. This prospective study aimed to assess the incidence and identify risk factors associated with IC in a neonatal intensive care unit (NICU) in Central India over a twoyear period from June 2022 to May 2024. Out of 563 blood cultures performed, 54 (9.59%) were positive for Candida species, with non-albicans Candida (NAC) species predominating. Key risk factors for IC included prematurity, very low birth weight, use of broad-spectrum antibiotics, central venous catheters, mechanical ventilation, parenteral nutrition, and extended NICU stay. Antifungal susceptibility testing revealed variable resistance among NAC species, emphasizing the need for tailored antifungal strategies. This study highlights the importance of vigilant monitoring, targeted interventions, and ongoing surveillance to improve outcomes for neonates at risk of IC.
- Subjects
VERY low birth weight; NEONATAL intensive care units; INTENSIVE care units; CENTRAL venous catheters; PARENTERAL feeding; INVASIVE candidiasis; CANDIDEMIA
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 7, p1627
- ISSN
0975-3583
- Publication type
Article