We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Enterococcus faecium Infections: An Emerging Threat.
- Authors
Kolambkar, Pranav P.; S., Ganesh Nayak; Prabhu, Kavitha; Boloor, Rekha; Bhat, Prasanna N.
- Abstract
Introduction: Enterococci are major cause of health care associated infections and are resistant to commonly used antibiotics like cephalosporins. The study aims to find the proportion and characteristics of Enterococcus faecium isolates among the enterococcal infections at a tertiary care hospital. Methods and Material: A prospective cohort study was conducted in a tertiary care hospital in Mangalore, Karnataka for a period of 6 months from June to November 2023. The enterococci were isolated and identified and tested for antibiotic susceptibility by the standard methods. Results: Among the 132 enterococcal strains isolated from the clinical samples, 68 (51.51%) were E. faecalis and 61(46.21%) were E. faecium. E. faecium was significantly isolated more from the urine samples and from the inpatients. Also, the resistance to ampicillin (57.4% vs 14.7%), high level gentamicin (54.1% vs 36.8%), nitrofurantoin (37.7% vs 8.8%) and vancomycin (11.5% vs 1.5%) was significantly more among the E. faecium isolates, compared to the E. faecalis isolates. Resistance to linezolid was not found in the current study. Conclusion: In the present study, E. faecium strains were isolated in higher proportion compared to other studies. Therefore, there is an emergent need to combat this increase in E. faecium infections and the associated antibiotic resistance by scrutinising and encouraging appropriate antibiotic use in the hospitals and community.
- Subjects
INDIA; ANTIBIOTICS; NITROFURANTOIN; ENTEROCOCCUS; DRUG resistance in microorganisms; BACTEREMIA; FISHER exact test; ENTEROCOCCAL infections; TREATMENT effectiveness; TERTIARY care; AMPICILLIN; VANCOMYCIN resistance; DESCRIPTIVE statistics; CHI-squared test; MANN Whitney U Test; LONGITUDINAL method; VANCOMYCIN; ENTEROCOCCUS faecium; URINALYSIS; GENTAMICIN; DISEASE susceptibility; COMPARATIVE studies; LINEZOLID; DATA analysis software
- Publication
Online Journal of Health & Allied Sciences, 2024, Vol 23, Issue 2, p1
- ISSN
0972-5997
- Publication type
Article