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- Title
Patient Participant Perspectives on Implementation of Long-Acting Cabotegravir and Rilpivirine: Results From the Cabotegravir and Rilpivirine Implementation Study in European Locations (CARISEL) Study.
- Authors
Gutner, Cassidy A.; van der Valk, Marc; Portilla, Joaquin; Jeanmaire, Eliette; Belkhir, Leïla; Lutz, Thomas; DeMoor, Rebecca; Trehan, Rekha; Scherzer, Jenny; Pascual-Bernáldez, Miguel; Ait-Khaled, Mounir; Hernandez, Beatriz; de Ruiter, Annemiek; Anand, Savita Bakhshi; Low, Emma L.; Hadi, Monica; Barnes, Nicola; Sevdalis, Nick; Mohammed, Perry; Czarnogorski, Maggie
- Abstract
Introduction: CARISEL is an implementation–effectiveness "hybrid" study examining the perspectives of people living with HIV-1 (patient study participants [PSPs]) on cabotegravir (CAB) plus rilpivirine (RPV) long-acting (LA) dosed every 2 months (Q2M) across 5 European countries. Methods: PSPs completed questionnaires on acceptability (Acceptability of Intervention Measure), appropriateness (Intervention Appropriateness Measure), and feasibility (Feasibility of Intervention Measure) at their first (Month [M] 1), third (M4), and seventh (M12) injection visits. Semistructured qualitative interviews were also conducted. Results: Overall, 437 PSPs were enrolled, of whom 430 received treatment. Median (interquartile range) age was 44 (37-51) years, 25.3% (n = 109/430) were female (sex at birth), and 21.9% (n = 94/430) were persons of color. Across time points, PSPs found CAB + RPV LA highly acceptable, appropriate, and feasible (mean scores ≥4.47/5). Qualitative data supported these observations. Conclusions: PSPs found CAB + RPV LA Q2M to be an acceptable, appropriate, and feasible treatment option.
- Subjects
PATIENTS' attitudes; PEOPLE of color; SEMI-structured interviews; SATISFACTION; HIV
- Publication
Journal of the International Association of Providers of AIDS Care, 2024, p1
- ISSN
2325-9582
- Publication type
Article
- DOI
10.1177/23259582241269837