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YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6649, doi. 10.3390/ijms22136649
By:
- Gao, Yunan;
- Sun, Yan;
- Ercan-Sencicek, Adife Gulhan;
- King, Justin S.;
- Akerberg, Brynn N.;
- Ma, Qing;
- Kontaridis, Maria I.;
- Pu, William T.;
- Lin, Zhiqiang
Publication type:
Article
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
Published in:
2011
By:
- Marin, Talita M.;
- Keith, Kimberly;
- Davies, Benjamin;
- Conner, David A.;
- Guha, Prajna;
- Kalaitzidis, Demetrios;
- Xue Wu;
- Lauriol, Jessica;
- Bo Wang;
- Bauer, Michael;
- Bronson, Roderick;
- Franchini, Kleber G.;
- Neel, Benjamin G.;
- Kontaridis, Maria I.;
- Wu, Xue;
- Wang, Bo
Publication type:
journal article
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
Published in:
Science Signaling, 2018, v. 11, n. 522, p. 1, doi. 10.1126/scisignal.aao1591
By:
- Zheng, Hong;
- Yu, Wen-Mei;
- Waclaw, Ronald R.;
- Kontaridis, Maria I.;
- Neel, Benjamin G.;
- Qu, Cheng-Kui
Publication type:
Article
DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.
Published in:
Science Signaling, 2017, v. 10, n. 468, p. 1, doi. 10.1126/scisignal.aaf5967
By:
- Simonson, Bridget;
- Subramanya, Vinita;
- Mun Chun Chan;
- Aifeng Zhang;
- Franchino, Hannabeth;
- Ottaviano, Filomena;
- Mishra, Manoj K.;
- Knight, Ashley C.;
- Hunt, Danielle;
- Ghiran, Ionita;
- Khurana, Tejvir S.;
- Kontaridis, Maria I.;
- Rosenzweig, Anthony;
- Das, Saumya
Publication type:
Article
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Published in:
Science Signaling, 2014, v. 7, n. 348, p. 1, doi. 10.1126/scisignal.2005262
By:
- Lauriol, Jessica;
- Keith, Kimberly;
- Jaffré, Fabrice;
- Couvillon, Anthony;
- Saci, Abdel;
- Goonasekera, Sanjeewa A.;
- McCarthy, Jason R.;
- Kessinger, Chase W.;
- Jianxun Wang;
- Qingen Ke;
- Kang, Peter M.;
- Molkentin, Jeffery D.;
- Carpenter, Christopher;
- Kontaridis, Maria I.
Publication type:
Article
The seventh international RASopathies symposium: Pathways to a cure—expanding knowledge, enhancing research, and therapeutic discovery.
Published in:
American Journal of Medical Genetics. Part A, 2022, v. 188, n. 6, p. 1915, doi. 10.1002/ajmg.a.62716
By:
- Kontaridis, Maria I.;
- Roberts, Amy E.;
- Schill, Lisa;
- Schoyer, Lisa;
- Stronach, Beth;
- Andelfinger, Gregor;
- Aoki, Yoko;
- Axelrad, Marni E.;
- Bakker, Annette;
- Bennett, Anton M.;
- Broniscer, Alberto;
- Castel, Pau;
- Chang, Caitlin A.;
- Cyganek, Lukas;
- Das, Tirtha K.;
- den Hertog, Jeroen;
- Galperin, Emilia;
- Garg, Shruti;
- Gelb, Bruce D.;
- Gordon, Kristiana
Publication type:
Article
Rapidly progressive hypertrophic cardiomyopathy in an infant with Noonan syndrome with multiple lentigines: Palliative treatment with a rapamycin analog.
Published in:
American Journal of Medical Genetics. Part A, 2015, v. 167A, n. 4, p. 744, doi. 10.1002/ajmg.a.36982
By:
- Hahn, Andreas;
- Lauriol, Jessica;
- Thul, Josef;
- Behnke‐Hall, Kachina;
- Logeswaran, Tushiha;
- Schänzer, Anne;
- Böğürcü, Nuray;
- Garvalov, Boyan K.;
- Zenker, Martin;
- Gelb, Bruce D.;
- von Gerlach, Susanne;
- Kandolf, Reinhard;
- Kontaridis, Maria I.;
- Schranz, Dietmar
Publication type:
Article
Stops along the RAS pathway in human genetic disease.
Published in:
Nature Medicine, 2006, v. 12, n. 3, p. 283, doi. 10.1038/nm0306-283
By:
- Bentires-Alj, Mohamed;
- Kontaridis, Maria I.;
- Neel, Benjamin G.
Publication type:
Article
A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.
Published in:
Scientific Reports, 2016, p. 20471, doi. 10.1038/srep20471
By:
- Breitkopf, Susanne B.;
- Yang, Xuemei;
- Begley, Michael J.;
- Kulkarni, Meghana;
- Chiu, Yu-Hsin;
- Turke, Alexa B.;
- Lauriol, Jessica;
- Yuan, Min;
- Qi, Jie;
- Engelman, Jeffrey A.;
- Hong, Pengyu;
- Kontaridis, Maria I.;
- Cantley, Lewis C.;
- Perrimon, Norbert;
- Asara, John M.
Publication type:
Article
Genetic and Phenotypic Analysis of Patients with Mucopolysaccharidosis type IIIB Co-morbid with Autism Spectrum Disorder.
Published in:
Gazi Medical Journal, 2024, v. 35, p. 6
By:
- Ercan-Şençiçek, A. Gülhan;
- Barak, Tanyeri;
- Rai, Devendra K.;
- Kaymakçalan, Hande;
- Kaya, İlyas;
- Erbilgin, Seda;
- Uytun, Merve Çıkılı;
- Öztop, Didem;
- Gümüş, Hakan;
- Per, Hüseyin;
- Ceylaner, Serdar;
- Aromolaran, Kelly;
- Bozkurt, İçten;
- Mishra-Gorur, Ketu;
- Kontaridis, Maria I.;
- Bilgüvar, Kaya;
- Kılınçaslan, Ayşe;
- Çağlayan, Ahmet Okay;
- Erson-Omay, E. Zeynep;
- Günel, Murat
Publication type:
Article
Lineage‐Specific Mesenchymal Stromal Cells Derived from Human iPSCs Showed Distinct Patterns in Transcriptomic Profile and Extracellular Vesicle Production.
Published in:
Advanced Science, 2024, v. 11, n. 28, p. 1, doi. 10.1002/advs.202308975
By:
- Winston, Tackla;
- Song, Yuanhui;
- Shi, Huaiyu;
- Yang, Junhui;
- Alsudais, Munther;
- Kontaridis, Maria I.;
- Wu, Yaoying;
- Gaborski, Thomas R.;
- Meng, Qinghe;
- Cooney, Robert N.;
- Ma, Zhen
Publication type:
Article
Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs (Adv. Sci. 17/2022)
Published in:
Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202270109
By:
- Li, Guoping;
- Manning, Aidan C.;
- Bagi, Alex;
- Yang, Xinyu;
- Gokulnath, Priyanka;
- Spanos, Michail;
- Howard, Jonathan;
- Chan, Patricia P.;
- Sweeney, Thadryan;
- Kitchen, Robert;
- Li, Haobo;
- Laurent, Brice D.;
- Aranki, Sary F.;
- Kontaridis, Maria I.;
- Laurent, Louise C.;
- Van Keuren‐Jensen, Kendall;
- Muehlschlegel, Jochen;
- Lowe, Todd M.;
- Das, Saumya
Publication type:
Article
Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs.
Published in:
Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202200829
By:
- Li, Guoping;
- Manning, Aidan C.;
- Bagi, Alex;
- Yang, Xinyu;
- Gokulnath, Priyanka;
- Spanos, Michail;
- Howard, Jonathan;
- Chan, Patricia P.;
- Sweeney, Thadryan;
- Kitchen, Robert;
- Li, Haobo;
- Laurent, Brice D.;
- Aranki, Sary F.;
- Kontaridis, Maria I.;
- Laurent, Louise C.;
- Van Keuren‐Jensen, Kendall;
- Muehlschlegel, Jochen;
- Lowe, Todd M.;
- Das, Saumya
Publication type:
Article
Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs (Adv. Sci. 17/2022).
Published in:
Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202200829
By:
- Li, Guoping;
- Manning, Aidan C.;
- Bagi, Alex;
- Yang, Xinyu;
- Gokulnath, Priyanka;
- Spanos, Michail;
- Howard, Jonathan;
- Chan, Patricia P.;
- Sweeney, Thadryan;
- Kitchen, Robert;
- Li, Haobo;
- Laurent, Brice D.;
- Aranki, Sary F.;
- Kontaridis, Maria I.;
- Laurent, Louise C.;
- Van Keuren‐Jensen, Kendall;
- Muehlschlegel, Jochen;
- Lowe, Todd M.;
- Das, Saumya
Publication type:
Article
Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.
Published in:
2016
By:
- Lauriol, Jessica;
- Cabrera, Janel R.;
- Roy, Ashbeel;
- Keith, Kimberly;
- Hough, Sara M.;
- Damilano, Federico;
- Wang, Bonnie;
- Segarra, Gabriel C.;
- Flessa, Meaghan E.;
- Miller, Lauren E.;
- Das, Saumya;
- Bronson, Roderick;
- Kyu-Ho Lee;
- Kontaridis, Maria I.;
- Lee, Kyu-Ho
Publication type:
journal article
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.
Published in:
2016
By:
- Jianxun Wang;
- Masayuki Mizui;
- Li-Fan Zeng;
- Bronson, Roderick;
- Finnell, Michele;
- Terhorst, Cox;
- Kyttaris, Vasileios C.;
- Tsokos, George C.;
- Zhong-Yin Zhang;
- Kontaridis, Maria I.;
- Wang, Jianxun;
- Mizui, Masayuki;
- Zeng, Li-Fan;
- Zhang, Zhong-Yin
Publication type:
journal article
Cardio-rheumatology: the cardiovascular, pharmacological, and surgical risks associated with rheumatological diseases in women.
Published in:
Canadian Journal of Physiology & Pharmacology, 2024, v. 102, n. 9, p. 511, doi. 10.1139/cjpp-2023-0420
By:
- Sommer, Samantha Le;
- Kontaridis, Maria I.
Publication type:
Article
SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.
Published in:
Journal of Cellular Physiology, 2004, v. 199, n. 2, p. 227, doi. 10.1002/jcp.10446
By:
- Christina Ivins Zito;
- Maria I. Kontaridis;
- Mara Fornaro;
- Geng-Shen Feng;
- Anton M. Bennett
Publication type:
Article
Protein tyrosine phosphatase 1B in metabolic and cardiovascular diseases: from mechanisms to therapeutics.
Published in:
Frontiers in Cardiovascular Medicine, 2024, p. 1, doi. 10.3389/fcvm.2024.1445739
By:
- Yan Sun;
- Dinenno, Frank A.;
- Peiyang Tang;
- Kontaridis, Maria I.
Publication type:
Article
SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49978-4
By:
- Chouhan, Surbhi;
- Sridaran, Dhivya;
- Weimholt, Cody;
- Luo, Jingqin;
- Li, Tiandao;
- Hodgson, Myles C.;
- Santos, Luana N.;
- Le Sommer, Samantha;
- Fang, Bin;
- Koomen, John M.;
- Seeliger, Markus;
- Qu, Cheng-Kui;
- Yart, Armelle;
- Kontaridis, Maria I.;
- Mahajan, Kiran;
- Mahajan, Nupam P.
Publication type:
Article
Biomimetic Nanomaterials for the Immunomodulation of the Cardiosplenic Axis Postmyocardial Infarction.
Published in:
Advanced Materials, 2024, v. 36, n. 8, p. 1, doi. 10.1002/adma.202304615
By:
- Bose, Rajendran JC;
- Kessinger, Chase W.;
- Dhammu, Tajinder;
- Singh, Toolika;
- Shealy, Miller W.;
- Ha, Khanh;
- Collandra, Rena;
- Himbert, Sebastian;
- Garcia, Fernando J.;
- Oleinik, Natalia;
- Xu, Bing;
- Vikas;
- Kontaridis, Maria I.;
- Rheinstädter, Maikel C.;
- Ogretmen, Besim;
- Menick, Donald R.;
- McCarthy, Jason R.
Publication type:
Article
In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178905
By:
- Wang, Jianxun;
- Chandrasekhar, Vasanth;
- Abbadessa, Giovanni;
- Yu, Yi;
- Schwartz, Brian;
- Kontaridis, Maria I.
Publication type:
Article

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