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- Title
Maturity onset diabetes of the young (MODY) - Screening, Diagnostik und Therapie.
- Authors
Kaser, Susanne; Resl, Michael
- Abstract
Maturity onset diabetes of the young (MODY) is a group of monogenetic diabetes types affecting up to 2 % all known diabetics. Transcription factor MODY (HNF1α, HNF4α), the most frequent forms of MODY, allow treatment with sulfonylureas, mutations of glucokinase (GCK-MODY) usually do not require any therapy. Especially in younger patients correct diagnosis of MODY often results in discontinuation of insulin therapy and initiation of a sulfonylurea. Accordingly, in patients with diabetes onset below age of 25 years, with a positive family history for diabetes and negative autoantibodies screening for MODY is recommended.
- Publication
Wiener Klinische Wochenschrift, 2016, Vol 128, p204
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-015-0938-9