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- Title
Comparative Effects of Hispidulin, Genistein, and Icariin with Estrogen on Bone Tissue in Ovariectomized Rats.
- Authors
Yang, Lijuan; Yu, Zixu; Qu, Haili; Li, Minmin
- Abstract
Icariin, Genistein, and Hispidulin have been proven to have estrogen-like and antiosteoporotic activity and can be potentially used for the treatment of osteoporosis. The present study found that Icariin, Genistein, and Hispidulin treatments, emulating estrogen, significantly contributed to bone density. Comparative effects of Icariin, Genistein, and Hispidulin with estrogen on in ovariectomized rats were investigated. Our results showed that genistein was found to have superior bone protective effects against osteoporosis among genistein, Icariin, and Hispidulin.
- Subjects
GENISTEIN; ESTROGEN; LABORATORY rats; OSTEOPOROSIS treatment; BONE density
- Publication
Cell Biochemistry & Biophysics, 2014, Vol 70, Issue 1, p485
- ISSN
1085-9195
- Publication type
Article
- DOI
10.1007/s12013-014-9945-0