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- Title
Traditional Herbal Medicine as Adjunctive Therapy for Nasopharyngeal Cancer: A Systematic Review and Meta-Analysis.
- Authors
Kim, Woojin; Lee, Won-Bock; Lee, Jungwoo; Min, Byung-Il; Lee, HyangSook; Cho, Seung-Hun
- Abstract
The effectiveness of traditional herbal medicine (THM) as treatment for nasopharyngeal cancer (NPC) has not been clearly demonstrated. The aim of this study is to assess the effectiveness of THM as adjunctive therapies for NPC using the results of randomized controlled trials (RCTs). Five electronic databases, including English and Chinese databases, were systematically searched up to February 2014. All RCTs involving traditional herbal medicine in combination with conventional cancer therapy for NPC were included. Twenty-two RCTs involving 2,298 NPC patients were systematically reviewed. Of these 22 studies, 15 on 1482 patients reported a significant increase in the number surviving patients with survivals of more than 1, 3, or 5 years. Seven studies on 595 patients reported a significant increase in immediate tumor response, and three studies on 505 patients reported a significant decrease in distant metastasis. This meta-analysis of 22 studies suggests that THM combined with conventional therapy can provide an effective adjunctive therapy for NPC. More research and well-designed, rigorous, large clinical trials are required to address these issues
- Subjects
TUMOR treatment; CINAHL database; CONFIDENCE intervals; DATABASES; DRUG toxicity; PATIENT aftercare; MEDICAL databases; INFORMATION storage &; retrieval systems; MEDICAL information storage &; retrieval systems; EVALUATION of medical care; BOTANIC medicine; CHINESE medicine; MEDLINE; META-analysis; METASTASIS; QUALITY assurance; NASOPHARYNX tumors; SURVIVAL; T cells; TRADITIONAL medicine; DATA analysis; RANDOMIZED controlled trials; CONTROL groups; ODDS ratio; DISEASE complications; DIAGNOSIS
- Publication
Integrative Cancer Therapies, 2015, Vol 14, Issue 3, p212
- ISSN
1534-7354
- Publication type
Article
- DOI
10.1177/1534735415572881