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Mg/Zn metal‐air primary batteries using silk fibroin‐ionic liquid polymer electrolytes.
Published in:
Nano Select, 2023, v. 4, n. 1, p. 90, doi. 10.1002/nano.202200200
By:
- Haskew, Mathew J.;
- Nikman, Shahin;
- O'Sullivan, Carys E.;
- Galeb, Hanaa A.;
- Halcovitch, Nathan R.;
- Hardy, John G.;
- Murphy, Samuel T.
Publication type:
Article
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.
Published in:
2010
By:
- Hampel, Harald;
- Frank, Richard;
- Broich, Karl;
- Teipel, Stefan J.;
- Katz, Russell G.;
- Hardy, John;
- Herholz, Karl;
- Bokde, Arun L. W.;
- Jessen, Frank;
- Hoessler, Yvonne C.;
- Sanhai, Wendy R.;
- Zetterberg, Henrik;
- Woodcock, Janet;
- Blennow, Kaj
Publication type:
journal article
Elevation of gangliosides in four brain regions from Parkinson's disease patients with a GBA mutation.
Published in:
NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00363-2
By:
- Blumenreich, Shani;
- Nehushtan, Tamar;
- Barav, Or B.;
- Saville, Jennifer T.;
- Dingjan, Tamir;
- Hardy, John;
- Fuller, Maria;
- Futerman, Anthony H.
Publication type:
Article
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability.
Published in:
NPJ Parkinson's Disease, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41531-019-0076-6
By:
- Reynolds, Regina H.;
- Botía, Juan;
- Nalls, Mike A.;
- Hardy, John;
- Gagliano Taliun, Sarah A.;
- Ryten, Mina
Publication type:
Article
Action Myoclonus and Seizure in Kufor‐Rakeb Syndrome.
Published in:
Movement Disorders Clinical Practice, 2018, v. 5, n. 2, p. 195, doi. 10.1002/mdc3.12570
By:
- Sina, Farzad;
- Rohani, Mohammad;
- Lang, Anthony E.;
- Fasano, Alfonso;
- Elahi, Elahe;
- Hardy, John;
- Bras, Jose;
- Alavi, Afagh
Publication type:
Article
Autonomic Dysfunction in Early Parkinson's Disease: Results from the United Kingdom Tracking Parkinson's Study.
Published in:
Movement Disorders Clinical Practice, 2017, v. 4, n. 4, p. 509, doi. 10.1002/mdc3.12454
By:
- Malek, Naveed;
- Lawton, Michael A.;
- Grosset, Katherine A.;
- Bajaj, Nin;
- Barker, Roger A.;
- Burn, David J.;
- Foltynie, Tom;
- Hardy, John;
- Morris, Huw R.;
- Williams, Nigel M.;
- Ben ‐ Shlomo, Yoav;
- Wood, Nicholas W.;
- Grosset, Donald G.
Publication type:
Article
The mouse that trolled.
Published in:
2015
By:
- Hardy, John
Publication type:
Opinion
Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer’s disease in a European population.
Published in:
Translational Psychiatry, 2024, p. 1, doi. 10.1038/s41398-024-03058-9
By:
- Simmonds, Emily;
- Leonenko, Ganna;
- Yaman, Umran;
- Bellou, Eftychia;
- Myers, Amanda;
- Morgan, Kevin;
- Brookes, Keeley;
- Hardy, John;
- Salih, Dervis;
- Escott-Price, Valentina
Publication type:
Article
APOE and AβPP Gene Variation in Cortical and Cerebrovascular Amyloid-β Pathology and Alzheimer's Disease: A Population-Based Analysis.
Published in:
Journal of Alzheimer's Disease, 2011, v. 26, n. 2, p. 377, doi. 10.3233/JAD-2011-102049
By:
- Peuralinna, Terhi;
- Tanskanen, Maarit;
- Mäkelä, Mira;
- Polvikoski, Tuomo;
- Paetau, Anders;
- Kalimo, Hannu;
- Sulkava, Raimo;
- Hardy, John;
- Lai, Shiao-Lin;
- Arepalli, Sampath;
- Hernandez, Dena;
- Traynor, Bryan J.;
- Singleton, Andrew;
- Tienari, Pentti J.;
- Myllykangas, Liisa
Publication type:
Article
Protected to Death.
Published in:
Journal of Alzheimer's Disease, 2010, v. 20, n. 2, p. 409, doi. 10.3233/JAD-2010-1416
By:
- Hardy, John;
- Gwinn, Katrina
Publication type:
Article
Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal.
Published in:
Journal of Alzheimer's Disease, 2006, v. 9, n. 3, p. 151, doi. 10.3233/JAD-2006-9S317
By:
- Hardy, John
Publication type:
Article
Alzheimer's disease: the amyloid cascade hypothesis: an update and reappraisal.
Published in:
2006
By:
- Hardy, John
Publication type:
journal article
Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer's disease.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99310-z
By:
- Kumar, Atul;
- Shoai, Maryam;
- Palmqvist, Sebastian;
- Stomrud, Erik;
- Hardy, John;
- Mattsson-Carlgren, Niklas;
- Hansson, Oskar
Publication type:
Article
CoExp: A Web Tool for the Exploitation of Co-expression Networks.
Published in:
Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.630187
By:
- García-Ruiz, Sonia;
- Gil-Martínez, Ana L.;
- Cisterna, Alejandro;
- Jurado-Ruiz, Federico;
- Reynolds, Regina H.;
- Cookson, Mark R.;
- Hardy, John;
- Ryten, Mina;
- Botía, Juan A.
Publication type:
Article
Li-Doped Bioactive Ceramics: Promising Biomaterials for Tissue Engineering and Regenerative Medicine.
Published in:
Journal of Functional Biomaterials, 2022, v. 13, n. 4, p. 162, doi. 10.3390/jfb13040162
By:
- Farmani, Ahmad Reza;
- Salmeh, Mohammad Ali;
- Golkar, Zahra;
- Moeinzadeh, Alaa;
- Ghiasi, Farzaneh Farid;
- Amirabad, Sara Zamani;
- Shoormeij, Mohammad Hasan;
- Mahdavinezhad, Forough;
- Momeni, Simin;
- Moradbeygi, Fatemeh;
- Ai, Jafar;
- Hardy, John G.;
- Mostafaei, Amir
Publication type:
Article
Electrical Stimulation to Enhance Wound Healing.
Published in:
Journal of Functional Biomaterials, 2021, v. 12, n. 2, p. 40, doi. 10.3390/jfb12020040
By:
- Rajendran, Saranya B.;
- Challen, Kirsty;
- Wright, Karen L.;
- Hardy, John G.
Publication type:
Article
In Situ Crosslinking Bionanocomposite Hydrogels with Potential for Wound Healing Applications.
Published in:
Journal of Functional Biomaterials, 2019, v. 10, n. 4, p. 50, doi. 10.3390/jfb10040050
By:
- Leone, Federica;
- Firlak, Melike;
- Challen, Kirsty;
- Bonnefin, Wayne;
- Onida, Barbara;
- Wright, Karen L.;
- Hardy, John G.
Publication type:
Article
Formulation of Antimicrobial Tobramycin Loaded PLGA Nanoparticles via Complexation with AOT.
Published in:
Journal of Functional Biomaterials, 2019, v. 10, n. 2, p. 26, doi. 10.3390/jfb10020026
By:
- Hill, Marcus;
- Cunningham, Richard N.;
- Hathout, Rania M.;
- Johnston, Christopher;
- Hardy, John G.;
- Migaud, Marie E.
Publication type:
Article
4D Printing: The Development of Responsive Materials Using 3D-Printing Technology.
Published in:
Pharmaceutics, 2023, v. 15, n. 12, p. 2743, doi. 10.3390/pharmaceutics15122743
By:
- Antezana, Pablo Edmundo;
- Municoy, Sofia;
- Ostapchuk, Gabriel;
- Catalano, Paolo Nicolás;
- Hardy, John G.;
- Evelson, Pablo Andrés;
- Orive, Gorka;
- Desimone, Martin Federico
Publication type:
Article
Electroresponsive Silk-Based Biohybrid Composites for Electrochemically Controlled Growth Factor Delivery.
Published in:
Pharmaceutics, 2020, v. 12, n. 8, p. 742, doi. 10.3390/pharmaceutics12080742
By:
- Magaz, Adrián;
- Ashton, Mark D.;
- Hathout, Rania M.;
- Li, Xu;
- Hardy, John G.;
- Blaker, Jonny J.
Publication type:
Article
Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications.
Published in:
Pharmaceutics, 2019, v. 11, n. 8, p. 379, doi. 10.3390/pharmaceutics11080379
By:
- Hill, Marcus;
- Twigg, Matthew;
- Sheridan, Emer A.;
- Hardy, John G.;
- Elborn, J. Stuart;
- Taggart, Clifford C.;
- Scott, Christopher J.;
- Migaud, Marie E.
Publication type:
Article
Aducanumab: a new phase in therapeutic development for Alzheimer's disease?
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 8, p. 1, doi. 10.15252/emmm.202114781
By:
- Lalli, Giovanna;
- Schott, Jonathan M;
- Hardy, John;
- De Strooper, Bart
Publication type:
Article
The amyloid hypothesis of Alzheimer's disease at 25 years.
Published in:
EMBO Molecular Medicine, 2016, v. 8, n. 6, p. 595, doi. 10.15252/emmm.201606210
By:
- Selkoe, Dennis J;
- Hardy, John
Publication type:
Article
A new way APP mismetabolism can lead to Alzheimer's disease.
Published in:
EMBO Molecular Medicine, 2011, v. 3, n. 5, p. 247, doi. 10.1002/emmm.201100139
By:
- Hardy, John;
- Guerreiro, Rita
Publication type:
Article
Identifying Genetic Factors in Parkinson Disease.
Published in:
JAMA: Journal of the American Medical Association, 2002, v. 287, n. 6, p. 715, doi. 10.1001/jama.287.6.715-a
By:
- Farrer, Matt;
- Hardy, John;
- Hutton, Mike;
- Maraganore, Demetrius;
- Tsuboi, Yoshio;
- Wszolek, Zbigniew K.
Publication type:
Article
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
Published in:
1998
By:
- Wu, William S.;
- Holmans, Peter;
- Wavrant-DeVrieze, Fabienne;
- Shears, Shantia;
- Kehoe, Patrick;
- Crook, Richard;
- Booth, Jeremy;
- Williams, Nigel;
- Perez-Tur, Jordi;
- Roehl, Kimberely;
- Fenton, Iain;
- Chartier-Harlin, Marie-Christine;
- Lovestone, Simon;
- Williams, Julie;
- Hutton, Mike;
- Hardy, John;
- Owen, Michael J.;
- Goate, Alison;
- Wu, W S;
- Holmans, P
Publication type:
journal article
Towards cascading genetic risk in Alzheimer's disease.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 8, p. 2680, doi. 10.1093/brain/awae176
By:
- Altmann, Andre;
- Aksman, Leon M;
- Oxtoby, Neil P;
- Young, Alexandra L;
- Alexander, Daniel C;
- Barkhof, Frederik;
- Shoai, Maryam;
- Hardy, John;
- Schott, Jonathan M
Publication type:
Article
Reply: Unblinding in the lecanemab trial in Alzheimer's disease.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 11, p. e101, doi. 10.1093/brain/awad201
By:
- Hardy, John;
- Mummery, Catherine
Publication type:
Article
Large-scale rare variant burden testing in Parkinson's disease.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 11, p. 4622, doi. 10.1093/brain/awad214
By:
- Makarious, Mary B;
- Lake, Julie;
- Pitz, Vanessa;
- Fu, Allen Ye;
- Guidubaldi, Joseph L;
- Solsberg, Caroline Warly;
- Bandres-Ciga, Sara;
- Leonard, Hampton L;
- Kim, Jonggeol Jeffrey;
- Billingsley, Kimberley J;
- Grenn, Francis P;
- Jerez, Pilar Alvarez;
- Alvarado, Chelsea X;
- Iwaki, Hirotaka;
- Ta, Michael;
- Vitale, Dan;
- Hernandez, Dena;
- Torkamani, Ali;
- Ryten, Mina;
- Hardy, John
Publication type:
Article
Reply: Lecanemab: turning point, or status quo? An ethics perspective.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 9, p. e73, doi. 10.1093/brain/awad102
By:
- Hardy, John;
- Mummery, Catherine
Publication type:
Article
Functional genomics provide key insights to improve the diagnostic yield of hereditary ataxia.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 7, p. 2869, doi. 10.1093/brain/awad009
By:
- Chen, Zhongbo;
- Tucci, Arianna;
- Cipriani, Valentina;
- Gustavsson, Emil K;
- Ibañez, Kristina;
- Reynolds, Regina H;
- Zhang, David;
- Vestito, Letizia;
- García, Alejandro Cisterna;
- Sethi, Siddharth;
- Brenton, Jonathan W;
- García-Ruiz, Sonia;
- Fairbrother-Browne, Aine;
- Gil-Martinez, Ana-Luisa;
- Consortium, Genomics England Research;
- Wood, Nick;
- Hardy, John A;
- Smedley, Damian;
- Houlden, Henry;
- Botía, Juan
Publication type:
Article
Association between the LRP1B and APOE loci in the development of Parkinson's disease dementia.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 5, p. 1873, doi. 10.1093/brain/awac414
By:
- Real, Raquel;
- Martinez-Carrasco, Alejandro;
- Reynolds, Regina H;
- Lawton, Michael A;
- Tan, Manuela M X;
- Shoai, Maryam;
- Corvol, Jean-Christophe;
- Ryten, Mina;
- Bresner, Catherine;
- Hubbard, Leon;
- Brice, Alexis;
- Lesage, Suzanne;
- Faouzi, Johann;
- Elbaz, Alexis;
- Artaud, Fanny;
- Williams, Nigel;
- Hu, Michele T M;
- Ben-Shlomo, Yoav;
- Grosset, Donald G;
- Hardy, John
Publication type:
Article
anti-amyloid therapy works for Alzheimer's disease: why has it taken so long and what is next?
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 4, p. 1240, doi. 10.1093/brain/awad049
By:
- Hardy, John;
- Mummery, Catherine
Publication type:
Article
Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 2, p. 690, doi. 10.1093/brain/awac128
By:
- Stevenson-Hoare, Joshua;
- Heslegrave, Amanda;
- Leonenko, Ganna;
- Fathalla, Dina;
- Bellou, Eftychia;
- Luckcuck, Lauren;
- Marshall, Rachel;
- Sims, Rebecca;
- Morgan, Bryan Paul;
- Hardy, John;
- Strooper, Bart de;
- Williams, Julie;
- Zetterberg, Henrik;
- Escott-Price, Valentina
Publication type:
Article
A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.
Published in:
2021
By:
- Magusali, Naciye;
- Graham, Andrew C;
- Piers, Thomas M;
- Panichnantakul, Pantila;
- Yaman, Umran;
- Shoai, Maryam;
- Reynolds, Regina H;
- Botia, Juan A;
- Brookes, Keeley J;
- Guetta-Baranes, Tamar;
- Bellou, Eftychia;
- Bayram, Sevinc;
- Sokolova, Dimitra;
- Ryten, Mina;
- Frigerio, Carlo Sala;
- Escott-Price, Valentina;
- Morgan, Kevin;
- Pocock, Jennifer M;
- Hardy, John;
- Salih, Dervis A
Publication type:
Journal Article
Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders.
Published in:
2020
By:
- Mencacci, Niccolò E;
- Reynolds, Regina;
- Ruiz, Sonia Garcia;
- Vandrovcova, Jana;
- Forabosco, Paola;
- Sánchez-Ferrer, Alvaro;
- Volpato, Viola;
- Consortium, UK Brain Expression;
- Consortium, International Parkinson's Disease Genomics;
- Weale, Michael E;
- Bhatia, Kailash P;
- Webber, Caleb;
- Hardy, John;
- Botía, Juan A;
- Ryten, Mina;
- UK Brain Expression Consortium;
- International Parkinson’s Disease Genomics Consortium
Publication type:
journal article
Informing disease modelling with brain-relevant functional genomic annotations.
Published in:
2019
By:
- Reynolds, Regina H;
- Hardy, John;
- Ryten, Mina;
- Taliun, Sarah A Gagliano;
- Gagliano Taliun, Sarah A
Publication type:
journal article
Genetic analysis of Mendelian mutations in a large UK population-based Parkinson's disease study.
Published in:
2019
By:
- Tan, Manuela M X;
- Malek, Naveed;
- Lawton, Michael A;
- Hubbard, Leon;
- Pittman, Alan M;
- Joseph, Theresita;
- Hehir, Jason;
- Swallow, Diane M A;
- Grosset, Katherine A;
- Marrinan, Sarah L;
- Bajaj, Nin;
- Barker, Roger A;
- Burn, David J;
- Bresner, Catherine;
- Foltynie, Thomas;
- Hardy, John;
- Wood, Nicholas;
- Ben-Shlomo, Yoav;
- Grosset, Donald G;
- Williams, Nigel M
Publication type:
journal article
Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy.
Published in:
2019
By:
- Guelfi, Sebastian;
- Botia, Juan A.;
- Thom, Maria;
- Ramasamy, Adaikalavan;
- Perona, Marina;
- Stanyer, Lee;
- Martinian, Lillian;
- Trabzuni, Daniah;
- Smith, Colin;
- Walker, Robert;
- Ryten, Mina;
- Reimers, Mark;
- Weale, Michael E.;
- Hardy, John;
- Matarin, Mar
Publication type:
journal article
A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK.
Published in:
2017
By:
- Morgan, Sarah;
- Shatunov, Aleksey;
- Sproviero, William;
- Jones, Ashley R.;
- Shoai, Maryam;
- Hughes, Deborah;
- Al Khleifat, Ahmad;
- Malaspina, Andrea;
- Morrison, Karen E.;
- Shaw, Pamela J.;
- Shaw, Christopher E.;
- Sidle, Katie;
- Orrell, Richard W.;
- Fratta, Pietro;
- Hardy, John;
- Pittman, Alan;
- Al-Chalabi, Ammar
Publication type:
journal article
Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia.
Published in:
2017
By:
- Mishra, Aniket;
- Ferrari, Raffaele;
- Heutink, Peter;
- Hardy, John;
- Pijnenburg, Yolande;
- Posthuma, Danielle;
- International FTD-Genomics Consortium
Publication type:
journal article
Multi-infarct dementia of Swedish type is caused by a 3'UTR mutation of COL4A1.
Published in:
2017
By:
- Siitonen, Maija;
- rjesson-Hanson, Anne Bö;
- Pöyhönen, Minna;
- Ora, Ari;
- Pasanen, Petra;
- Bras, Jose;
- Kern, Silke;
- Kern, Jürgen;
- Andersen, Oluf;
- Stanescu, Horia;
- Kleta, Robert;
- Baumann, Marc;
- Kalaria, Rajesh;
- Kalimo, Hannu;
- Singleton, Andy;
- Hardy, John;
- Viitanen, Matti;
- Myllykangas, Liisa;
- Guerreiro, Rita;
- Börjesson-Hanson, Anne
Publication type:
Letter
Alzheimer's disease: where next for anti-amyloid therapies?
Published in:
2017
By:
- Hardy, John;
- De Strooper, Bart
Publication type:
Editorial
Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology.
Published in:
2016
By:
- Ling, Helen;
- Kovacs, Gabor G;
- Vonsattel, Jean Paul G;
- Davey, Karen;
- Mok, Kin Y;
- Hardy, John;
- Morris, Huw R;
- Warner, Thomas T;
- Holton, Janice L;
- Revesz, Tamas
Publication type:
journal article
Reply: Glial mitochondropathy in infantile neuroaxonal dystrophy: pathophysiological and therapeutic implications.
Published in:
Brain: A Journal of Neurology, 2016, v. 139, n. 12, p. 1, doi. 10.1093/brain/aww185
By:
- Kinghorn, Kerri J.;
- Castillo-Quan, Jorge Iván;
- Li Li;
- Bhatia, Kailash P.;
- Abramov, Andrey Y.;
- Hardy, John;
- Partridge, Linda
Publication type:
Article
Is SIGMAR1 a confirmed FTD/MND gene?
Published in:
2015
By:
- Pickering-Brown, Stuart;
- Hardy, John;
- Bernard-Marissal, Nathalie;
- Médard, Jean-Jacques;
- Azzedine, Hamid;
- Chrast, Roman
Publication type:
commentary
First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression.
Published in:
2015
By:
- Cummings, Damian M.;
- Wenfei Liu;
- Portelius, Erik;
- Bayram, Sevinç¸;
- Yasvoina, Marina;
- Sui-Hin Ho;
- Smits, Hélène;
- Ali, Shabinah S.;
- Steinberg, Rivka;
- Pegasiou, Chrysia-Maria;
- James, Owain T.;
- Matarin, Mar;
- Richardson, Jill C.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Hardy, John A.;
- Salih, Dervis A.;
- Edwards, Frances A.
Publication type:
journal article
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction.
Published in:
2015
By:
- Kinghorn, Kerri J.;
- Castillo-Quan, Jorge Iván;
- Bartolome, Fernando;
- Angelova, Plamena R.;
- Li Li;
- Pope, Simon;
- Cochemé, Helena M.;
- Khan, Shabana;
- Asghari, Shabnam;
- Bhatia, Kailash P.;
- Hardy, John;
- Abramov, Andrey Y.;
- Partridge, Linda;
- Li, Li
Publication type:
journal article
Reply: Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
Published in:
Brain: A Journal of Neurology, 2015, v. 138, n. 5, p. e352, doi. 10.1093/brain/awu309
By:
- Mencacci, Niccolo E.;
- Pittman, Alan M.;
- Isaias, Ioannis U.;
- Hardy, John;
- Klebe, Stephan;
- Bhatia, Kailash P.;
- Wood, Nicholas W.
Publication type:
Article
Alzheimer disease PS-1 exon 9 deletion defined.
Published in:
Nature Medicine, 1999, v. 5, n. 10, p. 1090, doi. 10.1038/13383
By:
- Prihar, Guy;
- Verkkoniem, Auli;
- Perez-Tur, Jordi;
- Crook, Richard;
- Lincoln, Sarah;
- Houlden, Henry;
- Somer, Mirja;
- Paetau, Anders;
- Kalimo, Hannu;
- Grover, Andrew;
- Myllykangas, Liisa;
- Hutton, Mike;
- Hardy, John;
- Haltia, Matti
Publication type:
Article

Found: 579