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- Title
Surgical correction of tracheo-oesophageal fistula and oesophageal atresia in infants with VACTERL association: a retrospective case-control study.
- Authors
Morgan RD; O'Callaghan JM; Wagener S; Grant HW; Lakhoo K; Morgan, Robert D; O'Callaghan, John M; Wagener, Silke; Grant, Hugh W; Lakhoo, Kokila
- Abstract
<bold>Introduction: </bold>VACTERL is a rare, non-random association comprising at least three major component features defined by the acronym, and including Vertebral anomalies, Anorectal malformations, Cardiac defects, Tracheo-oEsophageal fistula with or without oesophageal atresia (TOF/OA), Renal abnormalities and Limb anomalies. The aim of this study was to compare the post-operative outcomes following surgical correction of TOF/OA in infants with VACTERL and isolated TOF/OA.<bold>Methods: </bold>A retrospective case-control study comparing infants with VACTERL (case group) versus infants with isolated TOF/OA (control group) that underwent surgical correction of TOF/OA at our centre between January 2006 and December 2011. Patient demographics, types of anomalies, operative techniques and post-operative outcomes were collected using inpatient and outpatient records.<bold>Results: </bold>We identified 30 consecutive infants with TOF/OA. Five infants had VACTERL (17 %) and 15 infants had isolated TOF/OA (50 %). There was no significant difference in the gestational age (P = 0.79), birth weight (P = 0.69) or operative repair (P = 0.14) between groups. Overall, surgical correction of TOF/OA led to satisfactory morbidity. Infants with VACTERL were not at higher risk of post-operative complications, such as oesophageal stricture (P = 0.17) or gastro-oesophageal reflux (P = 1.0), compared to infants with isolated TOF/OA.<bold>Conclusions: </bold>VACTERL association does not increase the risk of post-operative complications following TOF/OA repair.
- Publication
Pediatric Surgery International, 2012, Vol 28, Issue 10, p967
- ISSN
0179-0358
- Publication type
journal article