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- Title
Clinical feasibility of a myocardial signal intensity threshold-based semi-automated cardiac magnetic resonance segmentation method.
- Authors
Varga-Szemes, Akos; Muscogiuri, Giuseppe; Schoepf, U.; Wichmann, Julian; Suranyi, Pal; Cecco, Carlo; Cannaò, Paola; Renker, Matthias; Mangold, Stefanie; Fox, Mary; Ruzsics, Balazs; Schoepf, U Joseph; Wichmann, Julian L; De Cecco, Carlo N; Cannaò, Paola M; Fox, Mary A
- Abstract
<bold>Objectives: </bold>To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements.<bold>Methods: </bold>Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular (LV) volumes and mass (LVM) using conventional and threshold-based segmentations. Phase-contrast images were used to independently measure stroke volume (SV). LV parameters were evaluated by two independent readers.<bold>Results: </bold>Evaluation times using the conventional and threshold-based methods were 8.4 ± 1.9 and 4.2 ± 1.3 min, respectively (P < 0.0001). LV parameters measured by the conventional and threshold-based methods, respectively, were end-diastolic volume (EDV) 146 ± 59 and 134 ± 53 ml; end-systolic volume (ESV) 64 ± 47 and 59 ± 46 ml; SV 82 ± 29 and 74 ± 28 ml (flow-based 74 ± 30 ml); ejection fraction (EF) 59 ± 16 and 58 ± 17%; and LVM 141 ± 55 and 159 ± 58 g. Significant differences between the conventional and threshold-based methods were observed in EDV, ESV, and LVM mesurements; SV from threshold-based and flow-based measurements were in agreement (P > 0.05) but were significantly different from conventional analysis (P < 0.05). Excellent inter-observer agreement was observed.<bold>Conclusions: </bold>Threshold-based LV segmentation provides improved accuracy and faster assessment compared to conventional contour-based methods.<bold>Key Points: </bold>• Threshold-based left ventricular segmentation provides time-efficient assessment of left ventricular parameters • The threshold-based method can discriminate between blood and papillary muscles • This method provides improved accuracy compared to aortic flow measurements as a reference.
- Subjects
MAGNETIC resonance imaging; STROKE volume (Cardiac output); HEART diseases; PAPILLARY muscles; AORTA; HEART ventricle diseases; ALGORITHMS; COMPARATIVE studies; LEFT heart ventricle; HEART ventricles; RESEARCH methodology; MEDICAL cooperation; MYOCARDIUM; NUCLEAR magnetic resonance spectroscopy; RESEARCH; RESEARCH evaluation; PILOT projects; EVALUATION research; RESEARCH bias; MAGNETIC resonance angiography
- Publication
European Radiology, 2016, Vol 26, Issue 5, p1503
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-015-3952-4