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- Title
Exposed peptide core of IgA1 hinge region in IgA nephropathy.
- Authors
Kokubo, T; Hiki, Y; Iwase, H; Tanaka, A; Nishikido, J; Hotta, K; Kobayashi, Y
- Abstract
Background: The human IgA1 hinge region is a very unique O-linked glycopeptide, and its sialylation and galactosylation recently were reported to be defective in the serum IgA1 derived from patients with IgA nephropathy (IgAN). This study was performed to examine the underglycosylation of the IgA1 hinge region and consequent exposure of the peptide core in IgAN.
- Publication
Nephrology Dialysis Transplantation, 1999, Vol 14, Issue 1, p81
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/14.1.81