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- Title
The penetration of ceftazidime into peritoneal fluid in patients undergoing elective abdominal surgery.
- Authors
Corbett, C. R. R.; McFarland, R. J.; Spender, G. R.; Ryan, D. M.; Corbett, C R
- Abstract
Using paper discs we have made repeated observations during laparotomy in 31 patients after giving 1 g of ceftazidime intravenously. Samples of serum were obtained simultaneously. Rapid transfer of antibiotic occurred. Peak concentration in peritoneal fluid occurred within 10 minutes of injection (66·7 mg/l, S.E.±10·6), the concurrent mean serum level being 106·0 mg/l (S.E.±10·7). Thereafter levels in serum and peritoneal fluid fell roughly in parallel.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1985, Vol 16, Issue 2, p261
- ISSN
0305-7453
- Publication type
journal article