We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
细胞因子在脑缺血损伤中的作用研究进展.
- Authors
王芳; 霍星; 王国年; 刘晶晶; 刘天琳
- Abstract
Once cerebral ischemia happens, it could induce different levels of brain damage frequently. Ischemic brain tissue leads to a series of complex pathophysiological changes. A set of polypeptide cytokines play a capital role in the process of cerebral ischemia injury. Many kinds of cells can produce and secrete cytokines, including nerve cells. These cytokines have different expressions of phase and effect. Cerebral ischemia causes the expression and release of various cytokines,such as TNF-α, IL-1 , IL-6, IL-8, IL-1 0 and FKN. This event triggers the response concerned with injury and repair. These cytokines, which participate cerebral ischemia injury can reduce toxical or protective effect on central nervous system through a complex network of cytokines. Investigating their definite effect during the progression of cerebral ischemia injury will conduce to the clinical treatment of nervous system diseases. This article reviews the effect of cerebral ischemia injury of several capital cytokines.
- Publication
Progress in Modern Biomedicine, 2015, Vol 15, Issue 7, p1398
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2015.07.053