We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Epidemiology, clinical signs, histopathology and molecular characterization of canine leproid granuloma: a retrospective study of cases from Brazil.
- Authors
Conceição, Lissandro Gonçalves; Acha, Livia Maria Rosa; Borges, Alexandre Secorun; Assis, Fernanda G.; Loures, Fabricia Hallack; e Silva, Fabyano Fonseca
- Abstract
Thirty-eight cases of canine leproid granuloma were diagnosed between 2000 and 2008. Diagnosis was based upon clinical and histopathological findings and the presence of acid-fast bacilli in skin sections. The clinical lesions were localized predominantly on the pinnae and included papules, plaques and nodules, with or without ulceration. Boxer dogs were the breed most affected. Histopathological findings included nodular to diffuse pyogranulomatous, lymphoplasmocytic inflammatory infiltrates, with or without necrosis, localized in the dermis or subcutaneous tissue. The bacillary loading and morphology were variable among the lesions analysed. There was no significant correlation between bacterial load and histopathological pattern, dominant type of inflammatory infiltration or the amount of necrosis or giant cells. No correlation was observed between giant cells and histopathological pattern. In the majority of cases where a PCR-based assay was done, a novel mycobacterium species as the main aetiological agent was identified, as reported in previous studies.
- Subjects
BRAZIL; RETROSPECTIVE studies; GRANULOMA; DOG diseases; SKIN diseases; PRECANCEROUS conditions; POLYMERASE chain reaction; NECROSIS; DIAGNOSIS
- Publication
Veterinary Dermatology, 2011, Vol 22, Issue 3, p249
- ISSN
0959-4493
- Publication type
Article
- DOI
10.1111/j.1365-3164.2010.00934.x