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- Title
Deposition of mannan-binding protein in glomeruli of HIGA mice in the exacerbation of glomerulonephrites induced by lipopolysaccharide.
- Authors
UEMURA, KAZUHIDE; SHIMOSAWA, MAKIKO; ADACHI, HIDEKI; LIU, NING; MUSO, ERI; KAWASAKI, TOSHISUKE; ONO, TAKAHIKO
- Abstract
The article examines the involvement of mannan-binding protein (MBP), an innate host defense factor, in immunoglobulin A (IgA) nephropathy by using HIGA mice. HIGA mice were injected with lipopolysaccharide intraperitoneally. Results indicate that MBP is involved in the exacerbation of IgA nephropathy in the HIGA mice.
- Subjects
CARRIER proteins; IGA glomerulonephritis; POLYSACCHARIDES; GLOMERULONEPHRITIS; BIOLOGICAL transport; PROTEIN binding
- Publication
Nephrology, 2005, Vol 10, pA431
- ISSN
1320-5358
- Publication type
Article
- DOI
10.1111/j.1440-1797.2005.00513.x