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- Title
Evaluation and post-transplant management of children after multi-organ-with-kidney transplantation.
- Authors
Engen, Rachel M.; Lemoine, Caroline P.
- Abstract
Multi-organ transplantation involves the transplant of two or more organs from a single donor into a single recipient; in most cases, one of these organs is a kidney. Multi-organ transplantation is uncommon in pediatric transplantation but can be life-saving or significantly life-improving for children with rare diseases, including primary heart, liver, pancreas, or intestinal failure with secondary kidney failure, metabolic disorders, and genetic conditions causing multi-organ dysfunction. This manuscript reviews the current state of pediatric multi-organ transplantation that includes a kidney, with a focus on indications, evaluation, and key differences in management compared to kidney-alone transplantation. Guidelines and consensus statements for pediatric multi-organ transplantation are nonexistent; this review condenses reported statistics and peer-reviewed expert opinion while highlighting areas in need of further research.
- Subjects
KIDNEY transplantation; POSTOPERATIVE care; MULTIPLE organ failure; TREATMENT effectiveness; HEART transplantation; PANCREAS transplantation; LIVER transplantation; EVALUATION; CHILDREN
- Publication
Pediatric Nephrology, 2024, Vol 39, Issue 10, p2875
- ISSN
0931-041X
- Publication type
Article
- DOI
10.1007/s00467-024-06336-2