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- Title
Can Probiotics and Diet Promote Beneficial Immune Modulation and Purine Control in Coronavirus Infection?
- Authors
Morais, Ana H. A.; Passos, Thais S.; Maciel, Bruna L. L.; da Silva-Maia, Juliana K.
- Abstract
Infection caused by the SARS-CoV-2 coronavirus worldwide has led the World Health Organization to declare a COVID-19 pandemic. Because there is no cure or treatment for this virus, it is emergingly urgent to find effective and validated methods to prevent and treat COVID-19 infection. In this context, alternatives related to nutritional therapy might help to control the infection. This narrative review proposes the importance and role of probiotics and diet as adjunct alternatives among the therapies available for the treatment of this new coronavirus. This review discusses the relationship between intestinal purine metabolism and the use of Lactobacillus gasseri and low-purine diets, particularly in individuals with hyperuricemia, as adjuvant nutritional therapies to improve the immune system and weaken viral replication, assisting in the treatment of COVID-19. These might be promising alternatives, in addition to many others that involve adequate intake of vitamins, minerals and bioactive compounds from food.
- Subjects
THERAPEUTIC use of probiotics; PURINE metabolism; CORONAVIRUS diseases; DIET; EPIDEMICS; IMMUNE system; IMMUNITY; WORLD Health Organization; GUT microbiome; COVID-19
- Publication
Nutrients, 2020, Vol 12, Issue 6, p1737
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu12061737