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- Title
Rectal Cancer Complete Response Outcomes in a Community-Based Hospital Comparable with Large Cancer Centers When Multidisciplinary Approach to Rectal Cancer Is Used.
- Authors
GEISER, ANDREW J.; AL-KHAMIS, AHMED; PATEL, SUPRIYA; SUGRUE, JEREMY; BORSUK, DANIEL J.; MARECIK, SLAWOMIR; KOCHAR, KUNAL; PARK, JOHN J.
- Abstract
Achievement of pathologic complete response (pCR) in patients with locally advanced rectal cancer correlates with improved prognosis relative to non-pCR counterparts. Such correlations are not well established in the context of a community-based hospital. This study aims to examine pCR rates, recurrences, and survival data for locally advanced rectal cancer patients in community settings. A single-center retrospective chart review was performed at a community-based hospital. Study population consisted of 119 patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy, followed by surgical resection. Patients with a history of metastasis, inflammatory bowel disease, hereditary cancer syndromes, concurrent or prior malignancy, and emergent surgery were excluded. Twenty-four patients (20.2%) achieved pCR. Across both groups, all demographics and perioperative characteristics were comparable. The five-year survival was 73.7 per cent in the non-pCR group and 95.8 per cent in the pCR group (P = 0.0243). At five years, 27.7 per cent of the non-pCR group had a recurrence, as compared with none in the pCR group (P = 0.0018). Based on our study, we believe that a multidisciplinary approach to rectal cancer used at a community-based hospital can achieve oncological outcomes and survival benefits similar to those of larger academic tertiary care institutions.
- Subjects
RECTAL cancer; HEREDITARY cancer syndromes; INFLAMMATORY bowel diseases; CANCER relapse; CANCER treatment; COMBINED modality therapy; HOSPITALS; PROGNOSIS; RECTUM tumors; SPECIALTY hospitals; TREATMENT effectiveness; RETROSPECTIVE studies; TUMOR treatment
- Publication
American Surgeon, 2019, Vol 85, Issue 5, p530
- ISSN
0003-1348
- Publication type
journal article
- DOI
10.1177/000313481908500532