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Severe infections emerge from commensal bacteria by adaptive evolution.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.30637
By:
- Young, Bernadette C.;
- Chieh-Hsi Wu;
- Gordon, N. Claire;
- Cole, Kevin;
- Pric, James R.;
- Liu, Elian;
- Sheppard, Anna E.;
- Perera, Sanuki;
- Charlesworth, Jane;
- Golubchik, Tanya;
- Iqbal, Zamin;
- Bowden, Rory;
- Massey, Ruth C.;
- Paul, John;
- Crook, Derrick W.;
- Peto, Timothy E.;
- Walker, A. Sarah;
- Llewelyn, Martin J.;
- Wyllie, David H.;
- Wilson, Daniel J.
Publication type:
Article
High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01076-0
By:
- Dreyer, Viola;
- Mandal, Ayan;
- Dev, Prachi;
- Merker, Matthias;
- Barilar, Ivan;
- Utpatel, Christian;
- Nilgiriwala, Kayzad;
- Rodrigues, Camilla;
- Crook, Derrick W.;
- the CRyPTIC Consortium;
- Peto, Timothy E. A.;
- Walker, A. Sarah;
- Hoosdally, Sarah J.;
- Gibertoni Cruz, Ana L.;
- Carter, Joshua;
- Earle, Sarah;
- Kouchaki, Samaneh;
- Yang, Yang;
- Walker, Timothy M.;
- Fowler, Philip W.
Publication type:
Article
Ten-year longitudinal molecular epidemiology study of Escherichia coli and Klebsiella species bloodstream infections in Oxfordshire, UK.
Published in:
Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00947-2
By:
- Lipworth, Samuel;
- Vihta, Karina-Doris;
- Chau, Kevin;
- Barker, Leanne;
- George, Sophie;
- Kavanagh, James;
- Davies, Timothy;
- Vaughan, Alison;
- Andersson, Monique;
- Jeffery, Katie;
- Oakley, Sarah;
- Morgan, Marcus;
- Hopkins, Susan;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Walker, Ann Sarah;
- Stoesser, Nicole
Publication type:
Article
Temporal and Geographic Stability of the Serogroup-Specific Invasive Disease Potential of Streptococcus pneumoniae in Children.
Published in:
Journal of Infectious Diseases, 2004, v. 190, n. 7, p. 1203, doi. 10.1086/423820
By:
- Brueggemann, Angela B.;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Butler, Jay C.;
- Kristinsson, Karl G.;
- Spratt, Brian G.
Publication type:
Article
Negative epistasis between the malaria-protective effects of α<sup>+</sup>-thalassemia and the sickle cell trait.
Published in:
Nature Genetics, 2005, v. 37, n. 11, p. 1253, doi. 10.1038/ng1660
By:
- Williams, Thomas N.;
- Mwangi, Tabitha W.;
- Wambua, Sammy;
- Peto, Timothy E. A.;
- Weatherall, David J.;
- Gupta, Sunetra;
- Recker, Mario;
- Penman, Bridget S.;
- Uyoga, Sophie;
- Macharia, Alex;
- Mwacharo, Jedidah K.;
- Snow, Robert W.;
- Marsh, Kevin
Publication type:
Article
Within-Host Evolution of <i>Staphylococcus aureus</i> during Asymptomatic Carriage
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0061319
By:
- Golubchik, Tanya;
- Batty, Elizabeth M.;
- Miller, Ruth R.;
- Farr, Helen;
- Young, Bernadette C.;
- Larner-Svensson, Hanna;
- Fung, Rowena;
- Godwin, Heather;
- Knox, Kyle;
- Votintseva, Antonina;
- Everitt, Richard G.;
- Street, Teresa;
- Cule, Madeleine;
- Ip, Camilla L. C.;
- Didelot, Xavier;
- Peto, Timothy E. A.;
- Harding, Rosalind M.;
- Wilson, Daniel J.;
- Crook, Derrick W.;
- Bowden, Rory
Publication type:
Article
Reduction of Invasive Pneumococcal Disease 3 Years After the Introduction of the 13-Valent Conjugate Vaccine in the Oxfordshire Region of England.
Published in:
Journal of Infectious Diseases, 2014, v. 210, n. 7, p. 1001, doi. 10.1093/infdis/jiu213
By:
- Moore, Catrin E.;
- Paul, John;
- Foster, Dona;
- Mahar, Saeed A.;
- Griffiths, David;
- Knox, Kyle;
- Peto, Timothy E.;
- Walker, A. Sarah;
- Crook, Derrick W.
Publication type:
Article
Recombinational Switching of the Clostridium difficile S-Layer and a Novel Glycosylation Gene Cluster Revealed by Large-Scale Whole-Genome Sequencing.
Published in:
Journal of Infectious Diseases, 2013, v. 207, n. 4, p. 675, doi. 10.1093/infdis/jis734
By:
- Dingle, Kate E.;
- Didelot, Xavier;
- Ansari, M. Azim;
- Eyre, David W.;
- Vaughan, Alison;
- Griffiths, David;
- Ip, Camilla L. C.;
- Batty, Elizabeth M.;
- Golubchik, Tanya;
- Bowden, Rory;
- Jolley, Keith A.;
- Hood, Derek W.;
- Fawley, Warren N.;
- Walker, A. Sarah;
- Peto, Timothy E.;
- Wilcox, Mark H.;
- Crook, Derrick W.
Publication type:
Article
Capsular Serotype-Specific Attack Rates and Duration of Carriage of Streptococcus pneumoniae in a Population of Children.
Published in:
Journal of Infectious Diseases, 2006, v. 194, n. 5, p. 682, doi. 10.1086/505710
By:
- Sleeman, Karen L.;
- Griffiths, David;
- Shackley, Fiona;
- Diggle, Linda;
- Gupta, Sunetra;
- Maiden, Martin C.;
- Moxon, E. Richard;
- Crook, Derrick W.;
- Peto, Timothy E. A.
Publication type:
Article
A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.75046
By:
- Fowler, Philip W.;
- Wright, Carla;
- Spiers, Helen;
- Tingting Zhu;
- Baeten, Elisabeth M. L.;
- Hoosdally, Sarah W.;
- Gibertoni Cruz, Ana L.;
- Roohi, Aysha;
- Kouchaki, Samaneh;
- Walker, Timothy M.;
- Peto, Timothy E. A.;
- Miller, Grant;
- Lintott, Chris;
- Clifton, David;
- Crook, Derrick W.;
- Walker, A. Sarah
Publication type:
Article
A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Published in:
eLife, 2022, p. 1
By:
- Fowler, Philip W.;
- Wright, Carla;
- Spiers, Helen;
- Tingting Zhu;
- Baeten, Elisabeth M. L.;
- Hoosdally, Sarah W.;
- Gibertoni Cruz, Ana Luíza;
- Roohi, Aysha;
- Kouchaki, Samaneh;
- Walker, Timothy M.;
- Peto, Timothy E. A.;
- Miller, Grant;
- Lintott, Chris;
- Clifton, David;
- Crook, Derrick W.;
- Walker, A. Sarah
Publication type:
Article
FAMILIAL POLYCYSTIC OVARIES: A GENETIC DISEASE?
Published in:
Clinical Endocrinology, 1988, v. 29, n. 6, p. 593, doi. 10.1111/j.1365-2265.1988.tb03707.x
By:
- HAGUE, WILLIAM M.;
- ADAMS, JUDITH;
- REEDERS, STEPHEN T.;
- PETO, TIMOTHY E. A.;
- JACOBS, HOWARD S.
Publication type:
Article
end-to-end heterogeneous graph attention network for Mycobacterium tuberculosis drug-resistance prediction.
Published in:
Briefings in Bioinformatics, 2021, v. 22, n. 6, p. 1, doi. 10.1093/bib/bbab299
By:
- Yang, Yang;
- Walker, Timothy M;
- Kouchaki, Samaneh;
- Wang, Chenyang;
- Peto, Timothy E A;
- Crook, Derrick W;
- Consortium, CRYPTIC;
- Clifton, David A
Publication type:
Article
Evolutionary History of the Clostridium difficile Pathogenicity Locus.
Published in:
Genome Biology & Evolution, 2014, v. 6, n. 1, p. 36, doi. 10.1093/gbe/evt204
By:
- Dingle, Kate E.;
- Elliott, Briony;
- Robinson, Esther;
- Griffiths, David;
- Eyre, David W.;
- Stoesser, Nicole;
- Vaughan, Alison;
- Golubchik, Tanya;
- Fawley, Warren N.;
- Wilcox, Mark H.;
- Peto, Timothy E.;
- Walker, A. Sarah;
- Riley, Thomas V.;
- Crook, Derrick W.;
- Didelot, Xavier
Publication type:
Article
Ten Years of Population-Level Genomic Escherichia coli and Klebsiella pneumoniae Serotype Surveillance Informs Vaccine Development for Invasive Infections.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 12, p. 2276, doi. 10.1093/cid/ciab006
By:
- Lipworth, Samuel;
- Vihta, Karina-Doris;
- Chau, Kevin K;
- Kavanagh, James;
- Davies, Timothy;
- George, Sophie;
- Barker, Leanne;
- Vaughan, Ali;
- Andersson, Monique;
- Jeffery, Katie;
- Oakley, Sarah;
- Morgan, Marcus;
- Peto, Timothy E A;
- Crook, Derrick W;
- Walker, A Sarah;
- Stoesser, Nicole
Publication type:
Article
Patient and Strain Characteristics Associated With Clostridium difficile Transmission and Adverse Outcomes.
Published in:
Clinical Infectious Diseases, 2018, v. 67, n. 9, p. 1379, doi. 10.1093/cid/ciy302
By:
- Martin, Jessica S H;
- Eyre, David W;
- Fawley, Warren N;
- Griffiths, David;
- Davies, Kerrie;
- Mawer, Damian P C;
- Peto, Timothy E A;
- Crook, Derrick W;
- Walker, A Sarah;
- Wilcox, Mark H
Publication type:
Article
The Hospital Water Environment as a Reservoir for Carbapenem-Resistant Organisms Causing Hospital- Acquired Infections-A Systematic Review of the Literature.
Published in:
Clinical Infectious Diseases, 2017, v. 64, n. 10, p. 1435, doi. 10.1093/cid/cix132
By:
- Kizny Gordon, Alice E.;
- Mathers, Amy J.;
- Cheong, Elaine Y. L.;
- Gottlieb, Thomas;
- Kotay, Shireen;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Stoesser, Nicole
Publication type:
Article
Contribution to Clostridium Difficile Transmission of Symptomatic Patients With Toxigenic Strains Who Are Fecal Toxin Negative.
Published in:
Clinical Infectious Diseases, 2017, v. 64, n. 9, p. 1163, doi. 10.1093/cid/cix079
By:
- Mawer, Damian P. C.;
- Eyre, David W.;
- Griffiths, David;
- Fawley, Warren N.;
- Martin, Jessica S. H.;
- Quan, T. Phuong;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Walker, A. Sarah;
- Wilcox, Mark H.
Publication type:
Article
Reply to Mills and Linkin.
Published in:
2014
By:
- Price, James R.;
- Golubchik, Tanya;
- Wilson, Daniel J.;
- Crook, Derrick W.;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Paul, John;
- Llewelyn, Martin J.
Publication type:
Letter to the Editor
Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit.
Published in:
Clinical Infectious Diseases, 2014, v. 58, n. 5, p. 609, doi. 10.1093/cid/cit807
By:
- Price, James R.;
- Golubchik, Tanya;
- Cole, Kevin;
- Wilson, Daniel J.;
- Crook, Derrick W.;
- Thwaites, Guy E.;
- Bowden, Rory;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Paul, John;
- Llewelyn, Martin J.
Publication type:
Article
Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance mechanisms.
Published in:
PLoS Biology, 2022, v. 20, n. 8, p. 1, doi. 10.1371/journal.pbio.3001755
By:
- Crook, Derrick W.;
- Rodrigues, Camilla;
- Ismail, Nazir Ahmed;
- Mistry, Nerges;
- Iqbal, Zamin;
- Merker, Matthias;
- Moore, David;
- Walker, A. Sarah;
- Thwaites, Guy;
- Niemann, Stefan;
- Wilson, Daniel J.;
- Cirillo, Daniela Maria;
- Lachapelle, Alexander S.;
- Clifton, David A.;
- Peto, Timothy E. A.;
- Hunt, Martin;
- Knaggs, Jeff;
- Fowler, Philip W.;
- Earle, Sarah G.;
- Grazian, Clara
Publication type:
Article
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Published in:
PLoS Biology, 2022, v. 20, n. 8, p. 1, doi. 10.1371/journal.pbio.3001721
By:
- Crook, Derrick W.;
- Peto, Timothy E. A.;
- Hoosdally, Sarah J.;
- Cruz, Ana Lúıza Gibertoni;
- Walker, A. Sarah;
- Walker, Timothy M.;
- Fowler, Philip W.;
- Iqbal, Zamin;
- Cirillo, Daniela Maria;
- Brankin, Alice;
- Malone, Kerri M.;
- Hunt, Martin;
- Knaggs, Jeff;
- Mistry, Nerges;
- Rodrigues, Camilla;
- Moore, David;
- Ismail, Nazir Ahmed;
- Niemann, Stefan;
- Roohi, Aysha;
- Letcher, Brice
Publication type:
Article
Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine-learning approaches.
Published in:
JAC-Antimicrobial Resistance, 2024, v. 6, n. 2, p. 1, doi. 10.1093/jacamr/dlae037
By:
- Carter, Joshua J;
- Walker, Timothy M;
- Walker, A Sarah;
- Whitfield, Michael G;
- Morlock, Glenn P;
- Lynch, Charlotte I;
- Adlard, Dylan;
- Peto, Timothy E A;
- Posey, James E;
- Crook, Derrick W;
- Fowler, Philip W
Publication type:
Article
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Published in:
2021
By:
- Eyre, David W.;
- Lumley, Sheila F.;
- O'Donnell, Denise;
- Stoesser, Nicole E.;
- Matthews, Philippa C.;
- Howarth, Alison;
- Hatch, Stephanie B.;
- Marsden, Brian D.;
- Cox, Stuart;
- James, Tim;
- Cornall, Richard J.;
- Stuart, David I.;
- Screaton, Gavin;
- Ebner, Daniel;
- Crook, Derrick W.;
- Conlon, Christopher P.;
- Jeffery, Katie;
- Walker, Timothy M.;
- Peto, Timothy E. A.
Publication type:
journal article
Using linked electronic health records to report healthcare-associated infections.
Published in:
PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206860
By:
- Quan, T. Phuong;
- Hope, Russell;
- Clarke, Tiphanie;
- Moroney, Ruth;
- Butcher, Lisa;
- Knight, Peter;
- Crook, Derrick;
- Hopkins, Susan;
- Peto, Timothy E. A.;
- Johnson, Alan P.;
- Walker, A. Sarah
Publication type:
Article
DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.
Published in:
Bioinformatics, 2019, v. 35, n. 18, p. 3240, doi. 10.1093/bioinformatics/btz067
By:
- Yang, Yang;
- Walker, Timothy M;
- Walker, A Sarah;
- Wilson, Daniel J;
- Peto, Timothy E A;
- Crook, Derrick W;
- Shamout, Farah;
- Consortium, CRyPTIC;
- Zhu, Tingting;
- Clifton, David A
Publication type:
Article
Application of machine learning techniques to tuberculosis drug resistance analysis.
Published in:
Bioinformatics, 2019, v. 35, n. 13, p. 2276, doi. 10.1093/bioinformatics/bty949
By:
- Kouchaki, Samaneh;
- Yang, Yang;
- Walker, Timothy M;
- Walker, A Sarah;
- Wilson, Daniel J;
- Peto, Timothy E A;
- Crook, Derrick W;
- Consortium, CRyPTIC;
- Clifton, David A
Publication type:
Article
Multi-Label Random Forest Model for Tuberculosis Drug Resistance Classification and Mutation Ranking.
Published in:
Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.00667
By:
- Kouchaki, Samaneh;
- Yang, Yang;
- Lachapelle, Alexander;
- Walker, Timothy M.;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Clifton, David A.
Publication type:
Article
Risk Factors for Clostridium difficile Acquisition in Infants: Importance of Study Design.
Published in:
2013
By:
- Stoesser, Nicole E.;
- Martin, Jessica;
- Mawer, Damian;
- Eyre, David W.;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Crook, Derrick W.;
- Wilcox, Mark H.
Publication type:
Letter
Fidaxomicin Versus Vancomycin for Clostridium difficile Infection: Meta-analysis of Pivotal Randomized Controlled Trials.
Published in:
Clinical Infectious Diseases, 2012, v. 55, n. suppl_2, p. S93, doi. 10.1093/cid/cis499
By:
- Crook, Derrick W.;
- Walker, A. Sarah;
- Kean, Yin;
- Weiss, Karl;
- Cornely, Oliver A.;
- Miller, Mark A.;
- Esposito, Roberto;
- Louie, Thomas J.;
- Stoesser, Nicole E.;
- Young, Bernadette C.;
- Angus, Brian J.;
- Gorbach, Sherwood L.;
- Peto, Timothy E. A.
Publication type:
Article
Predictors of First Recurrence of Clostridium difficile Infection: Implications for Initial Management.
Published in:
Clinical Infectious Diseases, 2012, v. 55, n. suppl_2, p. S77
By:
- Eyre, David W.;
- Walker, A. Sarah;
- Wyllie, David;
- Dingle, Kate E.;
- Griffiths, David;
- Finney, John;
- O'Connor, Lily;
- Vaughan, Alison;
- Crook, Derrick W.;
- Wilcox, Mark H.;
- Peto, Timothy E. A.
Publication type:
Article
EFFECTS OF IRON AND DESFERRIOXAMINE ON THE GROWTH OF PLASMODIUM FALCIPARUM IN VITRO.
Published in:
British Journal of Haematology, 1987, v. 65, n. 2, p. 257, doi. 10.1111/j.1365-2141.1987.tb02284.x
By:
- Peto, Timothy E. A.;
- Thompson, Jane
Publication type:
Article

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