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- Title
Effect of Vaginal Microecological Disorders on the Increased Risk of Abnormal Cervical Cytology Among Women With Human Immunodeficiency Virus in China.
- Authors
Wang, Xiaolei; Zhang, Yuanyuan; Xiao, Jiang; Song, Chuan; Liu, Tingting; Liu, Jun; Zhao, Hongxin
- Abstract
Background Abnormal cervical cytology is commonly observed in women with human immunodeficiency virus (WWH). Methods A cross-sectional study was conducted with 130 WWH and 147 age-matched healthy controls, who underwent gynecological examinations at Beijing Ditan Hospital. The presence of abnormal cervical cytology in WWH was predicted after performing a logistic regression analysis. Results Multivariate logistic regression revealed 3 independent factors, among which CD4 cell count ≥350 cells/μL was the protective factor, while human papillomavirus infection and abnormal vaginal pH were the risk factors. Conclusions Vaginal microecological disorders can increase the risk of abnormal cervical cytology in WWH.
- Subjects
HIV; HUMAN papillomavirus; CD4 lymphocyte count; LOGISTIC regression analysis; PAPILLOMAVIRUS diseases; COLPOSCOPY
- Publication
Journal of Infectious Diseases, 2024, Vol 230, Issue 1, p61
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1093/infdis/jiae058