We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Bactericidal activity of topical antiseptics and their gargles against Bordetella pertussis.
- Authors
Suzuki, Takahisa; Kataoka, Hiroshi; Ida, Takashi; Kamachi, Kazunari; Mikuniya, Takeshi
- Abstract
Bordetella pertussis is the etiological agent of whooping cough, a common cause of respiratory illness in both children and adults. In the present study, we investigated the bactericidal activity of four antiseptics-povidone-iodine (PVP-I), benzethonium chloride (BEC), chlorhexidine gluconate (CHG) and benzalkonium chloride (BAC)-against B. pertussis ATCC9797 and clinical isolates. Among the topical antiseptics, PVP-I, BEC, and BAC, PVP-I and BAC in particular, showed high bactericidal activity, whereas CHG had low activity. PVP-I gargle also showed high bactericidal activity, similar to topical PVP-I. However, BEC gargle had low bactericidal activity. Our results indicate that topical PVP-I and BAC, and PVP-I gargle would be useful as effective antiseptics against B. pertussis.
- Subjects
BORDETELLA pertussis; WHOOPING cough; RESPIRATORY diseases; ANTISEPTICS; POVIDONE; IODINE
- Publication
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.), 2012, Vol 18, Issue 2, p272
- ISSN
1341-321X
- Publication type
Article
- DOI
10.1007/s10156-011-0312-4