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- Title
Laser therapy for treating cleft lip or/and palate scarring—a systematic review and meta-analysis.
- Authors
Sun, Yixin; Li, Ziming; Qi, Xiaoyu; Wang, Binghan; Yu, Nanze; Huang, Jiuzuo; Ting, Wenyun; Long, Xiao
- Abstract
This review aims to assess the efficacy and safety of laser therapy in managing scars resulting from cleft lip and/or palate (CL/P) repair surgeries, as well as to determine the optimal timing for intervention. A systematic search was conducted across four databases using a predefined search strategy. Studies included were randomized controlled trials, non-randomized studies, and case series focusing on laser therapy for CL/P scars. Data extraction and analysis were performed using Revman Software. A total of two randomized controlled trials, four non-randomized studies, and three case series were included in the analysis. The fractional CO2 laser was the most commonly utilized type of laser. Following laser therapy, there was a significant decrease in Vancouver Scar Scale (VSS) scores by 4.05 (95% CI, 2.10–5.99). Meta-analysis revealed that laser treatment groups exhibited a significantly lower mean VSS score (1.3; 95% CI, 0.02–2.67) compared to control groups. Moreover, initiating laser therapy intervention at one month postoperatively resulted in a significantly lower VSS score compared to initiation at three months postoperatively (difference of 1.70; 95% CI, 1.33–2.08). No severe complications were reported. Laser therapy demonstrates effectiveness and safety in improving CL/P scars, with earlier intervention yielding greater benefits.
- Subjects
LASER therapy; CLEFT lip; PALATE surgery; PALATE; SCARS; DATA extraction
- Publication
Lasers in Medical Science, 2024, Vol 39, Issue 1, p1
- ISSN
0268-8921
- Publication type
Article
- DOI
10.1007/s10103-024-04082-3