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- Title
Characterization of a novel highly pathogenic H5N2 avian influenza virus isolated from a duck in eastern China.
- Authors
Wu, Haibo; Peng, Xiaorong; Xu, Lihua; Jin, Changzhong; Cheng, Linfang; Lu, Xiangyun; Xie, Tiansheng; Yao, Hangping; Wu, Nanping
- Abstract
During surveillance for avian influenza viruses (AIVs) in live-poultry markets (LPMs) in eastern China in 2013, one H5N2 AIV was isolated from a duck. Phylogenetic analysis showed that the hemagglutinin of this strain belongs to clade 2.3.4 and received its genes from H5, H3 and H6 AIVs of poultry in China. The virulence of this strain was examined in chickens and mice, and it was found to be highly pathogenic in chickens but demonstrated moderate pathogenicity in mice. These results suggest that active surveillance of AIVs in LPMs should be used in an early warning system for avian influenza outbreaks.
- Subjects
CHINA; PATHOGENIC viruses; AVIAN influenza A virus; VIRUS isolation; DUCKS; ANIMALS; HEMAGGLUTININ; DISEASES
- Publication
Archives of Virology, 2014, Vol 159, Issue 12, p3377
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-014-2193-1