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- Title
Adverse Effects of Perfluorooctane Sulfonate on the Liver and Relevant Mechanisms.
- Authors
Wang, Pingwei; Liu, Dongge; Yan, Shuqi; Cui, Jiajing; Liang, Yujun; Ren, Shuping
- Abstract
Perfluorooctane sulfonate (PFOS) is a persistent, widely present organic pollutant. PFOS can enter the human body through drinking water, ingestion of food, contact with utensils containing PFOS, and occupational exposure to PFOS, and can have adverse effects on human health. Increasing research shows that the liver is the major target of PFOS, and that PFOS can damage liver tissue and disrupt its function; however, the exact mechanisms remain unclear. In this study, we reviewed the adverse effects of PFOS on liver tissue and cells, as well as on liver function, to provide a reference for subsequent studies related to the toxicity of PFOS and liver injury caused by PFOS.
- Subjects
PERFLUOROOCTANE sulfonate; LIVER cells; LIVER; OCCUPATIONAL exposure; HUMAN body; DRINKING water; HEPATOTOXICOLOGY
- Publication
Toxics, 2022, Vol 10, Issue 5, p265
- ISSN
2305-6304
- Publication type
Article
- DOI
10.3390/toxics10050265