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- Title
Parkinson's Disease and Occupation: Differences in Associations by Case Identification Method Suggest Referral Bias.
- Authors
Teschke, Kay; Marion, Stephen A.; Tsui, Joseph K.C.; Shen, Hui; Rugbjerg, Kathrine; Harris, M. Anne
- Abstract
Methods We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. Results With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social science, law and library jobs (OR = 1.8); farming and horticulture jobs (OR = 2.0); gas station jobs (OR = 2.6); and welders (OR = 3.0). The following had significantly decreased risks: management and administration jobs (OR = 0.70); and other health care jobs (OR = 0.44). Conclusions These results were consistent with other findings for social science and farming occupations. Risks for teaching, medicine and health occupations were not elevated, unlike our previous clinic-based study. This underscores the value of population-based over clinic-based samples. Occupational studies may be particularly susceptible to referral bias because social networks may spread preferentially via jobs. Am. J. Ind. Med. 57:163-171, 2014. © 2013 Wiley Periodicals, Inc.
- Subjects
SOCIAL sciences; RISK assessment; HEALTH occupations schools; THRESHOLD limit values (Industrial toxicology); SELECTION bias (Statistics)
- Publication
American Journal of Industrial Medicine, 2014, Vol 57, Issue 2, p163
- ISSN
0271-3586
- Publication type
Article
- DOI
10.1002/ajim.22272