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- Title
Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France.
- Authors
Rodriguez, Christophe; Gricourt, Guillaume; Ndebi, Melissa; Demontant, Vanessa; Poiteau, Lila; Burrel, Sonia; Boutolleau, David; Woerther, Paul-Louis; Calvez, Vincent; Stroer, Sebastian; Pawlotsky, Jean-Michel
- Abstract
We report the discovery of a new orthobunyavirus, Cristoli virus, by means of shotgun metagenomics. The virus was identified in an immunodepressed patient with fatal encephalitis. Full-length genome sequencing revealed high-level expression of a virulence factor, possibly explaining the severity of the infection. The patient's recent history suggests circulation in France.
- Subjects
FRANCE; ENCEPHALITIS; VIRUSES; NUCLEOTIDE sequencing; METAGENOMICS
- Publication
Emerging Infectious Diseases, 2020, Vol 26, Issue 6, p1287
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2606.191431