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Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites.
Published in:
Clinical & Translational Medicine, 2015, v. 4, n. 1, p. 1, doi. 10.1186/s40169-015-0054-5
By:
- Swindell, William R;
- Sarkar, Mrinal K;
- Stuart, Philip E;
- Voorhees, John J;
- Elder, James T;
- Johnston, Andrew;
- Gudjonsson, Johann E
Publication type:
Article
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.
Published in:
Nature Genetics, 2015, v. 47, n. 9, p. 1085, doi. 10.1038/ng.3379
By:
- Deutsch, Aaron J;
- Hu, Xinli;
- Gladman, Dafna D;
- Rantapää-Dahlqvist, Solbritt;
- Worthington, Jane;
- Klareskog, Lars;
- Knapp, Michael;
- Stuart, Philip E;
- Eyre, Stephen;
- Onengut-Gumuscu, Suna;
- Becker, Jessica;
- Gregersen, Peter K;
- Gutierrez-Achury, Javier;
- Wijmenga, Cisca;
- Rich, Stephen S;
- Gockel, Ines;
- Martin, Javier;
- Okada, Yukinori;
- Elder, James T;
- Sunyaev, Shamil R
Publication type:
Article
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
Published in:
Nature Genetics, 2012, v. 44, n. 12, p. 1341, doi. 10.1038/ng.2467
By:
- Tsoi, Lam C;
- Spain, Sarah L;
- Knight, Jo;
- Ellinghaus, Eva;
- Stuart, Philip E;
- Capon, Francesca;
- Ding, Jun;
- Li, Yanming;
- Tejasvi, Trilokraj;
- Gudjonsson, Johann E;
- Kang, Hyun M;
- Allen, Michael H;
- McManus, Ross;
- Novelli, Giuseppe;
- Samuelsson, Lena;
- Schalkwijk, Joost;
- Ståhle, Mona;
- Burden, A David;
- Smith, Catherine H;
- Cork, Michael J
Publication type:
Article
Genome-wide association analysis identifies three psoriasis susceptibility loci.
Published in:
Nature Genetics, 2010, v. 42, n. 11, p. 1000, doi. 10.1038/ng.693
By:
- Stuart, Philip E.;
- Nair, Rajan P.;
- Ellinghaus, Eva;
- Ding, Jun;
- Tejasvi, Trilokraj;
- Gudjonsson, Johann E.;
- Yun Li;
- Weidinger, Stephan;
- Eberlein, Bernadette;
- Gieger, Christian;
- Wichmann, H. Erich;
- Kunz, Manfred;
- Ike, Robert;
- Krueger, Gerald G.;
- Bowcock, Anne M.;
- Mrowietz, Ulrich;
- Lim, Henry W.;
- Voorhees, John J.;
- Abecasis, Gonçalo R.;
- Weichenthal, Michael
Publication type:
Article
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
Published in:
Nature Genetics, 2010, v. 42, n. 11, p. 991, doi. 10.1038/ng.689
By:
- Ellinghaus, Eva;
- Ellinghaus, David;
- Stuart, Philip E.;
- Nair, Rajan P.;
- Debrus, Sophie;
- Raelson, John V.;
- Belouchi, Majid;
- Fournier, Hélène;
- Reinhard, Claudia;
- Jun Ding;
- Yun Li;
- Tejasvi, Trilokraj;
- Gudjonsson, Johann;
- Stoll, Stefan W.;
- Voorhees, John J.;
- Lambert, Sylviane;
- Weidinger, Stephan;
- Eberlein, Bernadette;
- Kunz, Manfred;
- Rahman, Proton
Publication type:
Article
Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways.
Published in:
Nature Genetics, 2009, v. 41, n. 2, p. 199, doi. 10.1038/ng.311
By:
- Nair, Rajan P.;
- Duffin, Kristina Callis;
- Helms, Cynthia;
- 4, Jun Ding;
- Stuart, Philip E.;
- Goldgar, David;
- Gudjonsson, Johann E.;
- Yun Li;
- Tejasvi, Trilokraj;
- Bing-Jian Feng;
- Ruether, Andreas;
- Schreiber, Stefan;
- Weichenthal, Michael;
- Gladman, Dafna;
- Rahman, Proton;
- Schrodi, Steven J.;
- Prahalad, Sampath;
- Guthery, Stephen L.;
- Fischer, Judith;
- Liao, Wilson
Publication type:
Article
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.
Published in:
Nature Genetics, 2009, v. 41, n. 2, p. 211, doi. 10.1038/ng.313
By:
- de Cid, Rafael;
- Riveira-Munoz, Eva;
- Zeeuwen, Patrick L. J. M.;
- Robarge, Jason;
- Liao, Wilson;
- Dannhauser, Emma N.;
- Giardina, Emiliano;
- Stuart, Philip E.;
- Nair, Rajan;
- Helms, Cynthia;
- Escaramís, Georgia;
- Ballana, Ester;
- Martín-Ezquerra, Gemma;
- den Heijer, Martin;
- Kamsteeg, Marijke;
- Joosten, Irma;
- Eichler, Evan E.;
- Lázaro, Conxi;
- Pujol, Ramón M.;
- Armengol, Lluís
Publication type:
Article
Heterogeneity of Inflammatory and Cytokine Networks in Chronic Plaque Psoriasis.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0034594
By:
- Swindell, William R.;
- Xianying Xing;
- Stuart, Philip E.;
- Chen, Cynthia S.;
- Aphale, Abhishek;
- Nair, Rajan P.;
- Voorhees, John J.;
- Elder, James T.;
- Johnston, Andrew;
- Gudjonsson, Johann E.
Publication type:
Article
Genetic evidence for involvement of the IL23 pathway in Thai psoriatics.
Published in:
Archives of Dermatological Research, 2010, v. 302, n. 2, p. 139, doi. 10.1007/s00403-009-0986-y
By:
- Nair, Rajan P.;
- Stuart, Philip E.;
- Kullavanijaya, Preya;
- Kullavanijaya, Prisana;
- Tejasvi, Trilokraj;
- Voorhees, John J.;
- Elder, James T.
Publication type:
Article
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.72452
By:
- Martin, Susan;
- Tyrrell, Jessica;
- Thomas, E. Louise;
- Bown, Matthew J.;
- Wood, Andrew R.;
- Beaumont, Robin N.;
- Tsoi, Lam C.;
- Stuart, Philip E.;
- Elder, James T.;
- Law, Philip;
- Houlston, Richard;
- Kabrhel, Christopher;
- Papadimitriou, Nikos;
- Gunter, Marc J.;
- Bull, Caroline J.;
- Bell, Joshua A.;
- Vincent, Emma E.;
- Sattar, Naveed;
- Dunlop, Malcolm G.;
- Tomlinson, Ian P. M.
Publication type:
Article
Fine mapping of eight psoriasis susceptibility loci.
Published in:
European Journal of Human Genetics, 2015, v. 23, n. 6, p. 844, doi. 10.1038/ejhg.2014.172
By:
- Das, Sayantan;
- Stuart, Philip E;
- Ding, Jun;
- Tejasvi, Trilokraj;
- Li, Yanming;
- Tsoi, Lam C;
- Chandran, Vinod;
- Fischer, Judith;
- Helms, Cynthia;
- Duffin, Kristina Callis;
- Voorhees, John J;
- Bowcock, Anne M;
- Krueger, Gerald G;
- Lathrop, G Mark;
- Nair, Rajan P;
- Rahman, Proton;
- Abecasis, Goncalo R;
- Gladman, Dafna;
- Elder, James T
Publication type:
Article
Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC.
Published in:
Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00304
By:
- Patrick, Matthew T.;
- Stuart, Philip E.;
- Raja, Kalpana;
- Chi, Sunyi;
- He, Zhi;
- Voorhees, John J.;
- Tejasvi, Trilokraj;
- Gudjonsson, Johann E.;
- Kahlenberg, J. Michelle;
- Chandran, Vinod;
- Rahman, Proton;
- Gladman, Dafna D.;
- Nair, Rajan P.;
- Elder, James T.;
- Tsoi, Lam C.
Publication type:
Article
Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era.
Published in:
BMC Medical Genomics, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1755-8794-7-27
By:
- Swindell, William R.;
- Stuart, Philip E.;
- Sarkar, Mrinal K.;
- Voorhees, John J.;
- Elder, James T.;
- Johnston, Andrew;
- Gudjonsson, Johann E.
Publication type:
Article
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.
Published in:
Nature Communications, 2017, v. 8, n. 5, p. 15382, doi. 10.1038/ncomms15382
By:
- Tsoi, Lam C.;
- Stuart, Philip E.;
- Tian, Chao;
- Gudjonsson, Johann E.;
- Das, Sayantan;
- Zawistowski, Matthew;
- Ellinghaus, Eva;
- Barker, Jonathan N.;
- Chandran, Vinod;
- Dand, Nick;
- Duffin, Kristina Callis;
- Enerbäck, Charlotta;
- Esko, Tõnu;
- Franke, Andre;
- Gladman, Dafna D.;
- Hoffmann, Per;
- Kingo, Külli;
- Kõks, Sulev;
- Krueger, Gerald G.;
- Lim, Henry W.
Publication type:
Article
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.
Published in:
Nature Communications, 2015, v. 6, n. 5, p. 7001, doi. 10.1038/ncomms8001
By:
- Tsoi, Lam C.;
- Spain, Sarah L.;
- Ellinghaus, Eva;
- Stuart, Philip E.;
- Capon, Francesca;
- Knight, Jo;
- Tejasvi, Trilokraj;
- Kang, Hyun M.;
- Allen, Michael H.;
- Lambert, Sylviane;
- Stoll, Stefan W.;
- Weidinger, Stephan;
- Gudjonsson, Johann E.;
- Koks, Sulev;
- Kingo, Külli;
- Esko, Tonu;
- Das, Sayantan;
- Metspalu, Andres;
- Weichenthal, Michael;
- Enerback, Charlotta
Publication type:
Article
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.
Published in:
Genome Biology, 2015, v. 16, n. 1, p. 24, doi. 10.1186/s13059-014-0570-4
By:
- Tsoi, Lam C.;
- Iyer, Matthew K.;
- Stuart, Philip E.;
- Swindell, William R.;
- Gudjonsson, Johann E.;
- Tejasvi, Trilokraj;
- Sarkar, Mrinal K.;
- Li, Bingshan;
- Ding, Jun;
- Voorhees, John J.;
- Kang, Hyun M.;
- Nair, Rajan P.;
- Chinnaiyan, Arul M.;
- Abecasis, Goncalo R.;
- Elder, James T.
Publication type:
Article
A Single SNP Surrogate for Genotyping HLA-C*06:02 in Diverse Populations.
Published in:
Journal of Investigative Dermatology, 2015, v. 135, n. 4, p. 1177, doi. 10.1038/jid.2014.517
By:
- Stuart, Philip E;
- Tejasvi, Trilokraj;
- Shaiq, Pakeeza A;
- Kullavanijaya, Preya;
- Qamar, Raheel;
- Raja, Ghazala K;
- Li, Yanming;
- Voorhees, John J;
- Abecasis, Gonçalo R;
- Elder, James T;
- Nair, Rajan P
Publication type:
Article
Transcriptome Analysis of Psoriasis in a Large Case-Control Sample: RNA-Seq Provides Insights into Disease Mechanisms.
Published in:
Journal of Investigative Dermatology, 2014, v. 134, n. 7, p. 1828, doi. 10.1038/jid.2014.28
By:
- Li, Bingshan;
- Tsoi, Lam C;
- Swindell, William R;
- Gudjonsson, Johann E;
- Tejasvi, Trilokraj;
- Johnston, Andrew;
- Ding, Jun;
- Stuart, Philip E;
- Xing, Xianying;
- Kochkodan, James J;
- Voorhees, John J;
- Kang, Hyun M;
- Nair, Rajan P;
- Abecasis, Goncalo R;
- Elder, James T
Publication type:
Article
Association of β-Defensin Copy Number and Psoriasis in Three Cohorts of European Origin.
Published in:
Journal of Investigative Dermatology, 2012, v. 132, n. 10, p. 2407, doi. 10.1038/jid.2012.191
By:
- Stuart, Philip E;
- Hüffmeier, Ulrike;
- Nair, Rajan P;
- Palla, Raquel;
- Tejasvi, Trilokraj;
- Schalkwijk, Joost;
- Elder, James T;
- Reis, Andre;
- Armour, John A L
Publication type:
Article
Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL.
Published in:
Journal of Investigative Dermatology, 2012, v. 132, n. 4, p. 1133, doi. 10.1038/jid.2011.415
By:
- Ellinghaus, Eva;
- Stuart, Philip E;
- Ellinghaus, David;
- Nair, Rajan P;
- Debrus, Sophie;
- Raelson, John V;
- Belouchi, Majid;
- Tejasvi, Trilokraj;
- Li, Yanming;
- Tsoi, Lam C;
- Onken, Anna T;
- Esko, Tonu;
- Metspalu, Andres;
- Rahman, Proton;
- Gladman, Dafna D;
- Bowcock, Anne M;
- Helms, Cynthia;
- Krueger, Gerald G;
- Koks, Sulev;
- Kingo, Külli
Publication type:
Article
TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis.
Published in:
Journal of Investigative Dermatology, 2012, v. 132, n. 3 part 1, p. 593, doi. 10.1038/jid.2011.376
By:
- Tejasvi, Trilokraj;
- Stuart, Philip E;
- Chandran, Vinod;
- Voorhees, John J;
- Gladman, Dafna D;
- Rahman, Proton;
- Elder, James T;
- Nair, Rajan P
Publication type:
Article
Meta-Analysis Confirms the LCE3C_LCE3B Deletion as a Risk Factor for Psoriasis in Several Ethnic Groups and Finds Interaction with HLA-Cw6.
Published in:
Journal of Investigative Dermatology, 2011, v. 131, n. 5, p. 1105, doi. 10.1038/jid.2010.350
By:
- Riveira-Munoz, Eva;
- Su-Min He;
- Escaramís, Georgia;
- Stuart, Philip E.;
- Hüffmeier, Ulrike;
- Lee, Catherine;
- Kirby, Brian;
- Oka, Akira;
- Giardina, Emiliano;
- Liao, Wilson;
- Bergboer, Judith;
- Kainu, Kati;
- de Cid, Rafael;
- Munkhbat, Batmunkh;
- Zeeuwen, Patrick L. J. M.;
- Armour, John A. L.;
- Poon, Annie;
- Mabuchi, Tomotaka;
- Ozawa, Akira;
- Zawirska, Agnieszka
Publication type:
Article
Molecular Dissection of Psoriasis: Integrating Genetics and Biology.
Published in:
Journal of Investigative Dermatology, 2010, v. 130, n. 5, p. 1213, doi. 10.1038/jid.2009.319
By:
- Elder, James T.;
- Bruce, Allen T.;
- Gudjonsson, Johann E.;
- Johnston, Andrew;
- Stuart, Philip E.;
- Tejasvi, Trilokraj;
- Voorhees, John J.;
- Abecasis, Gonçalo R.;
- Nair, Rajan P.
Publication type:
Article
Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis.
Published in:
Journal of Investigative Dermatology, 2008, v. 128, n. 7, p. 1653, doi. 10.1038/sj.jid.5701255
By:
- Nair, Rajan P;
- Ruether, Andreas;
- Stuart, Philip E;
- Jenisch, Stefan;
- Tejasvi, Trilokraj;
- Hiremagalore, Ravi;
- Schreiber, Stefan;
- Kabelitz, Dieter;
- Lim, Henry W;
- Voorhees, John J;
- Christophers, Enno;
- Elder, James T;
- Weichenthal, Michael
Publication type:
Article
Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin‐17 and Janus Kinase–Signal Transducers and Activators of Transcription Signaling.
Published in:
Annals of Neurology, 2023, v. 94, n. 2, p. 384, doi. 10.1002/ana.26672
By:
- Patrick, Matthew T.;
- Nair, Rajan P.;
- He, Kevin;
- Stuart, Philip E.;
- Billi, Allison C.;
- Zhou, Xiang;
- Gudjonsson, Johann E.;
- Oksenberg, Jorge R.;
- Elder, James T.;
- Tsoi, Lam C.
Publication type:
Article
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 21, p. 4301, doi. 10.1093/hmg/ddx328
By:
- Dand, Nick;
- Mucha, Sören;
- Tsoi, Lam C.;
- Mahil, Satveer K.;
- Stuart, Philip E.;
- Arnold, Andreas;
- Baurecht, Hansjörg;
- Burden, A. David;
- Duffin, Kristina Callis;
- Chandran, Vinod;
- Curtis, Charles J.;
- Barker, Jonathan N.
Publication type:
Article
Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 9, p. 1807, doi. 10.1093/hmg/ddt034
By:
- Johnston, Andrew;
- Xing, Xianying;
- Swindell, William R.;
- Kochkodan, James;
- Riblett, MaryBeth;
- Nair, Rajan P.;
- Stuart, Philip E.;
- Ding, Jun;
- Voorhees, John J.;
- Elder, James T.;
- Gudjonsson, Johann E.
Publication type:
Article
Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06672-6
By:
- Patrick, Matthew T.;
- Stuart, Philip E.;
- Raja, Kalpana;
- Gudjonsson, Johann E.;
- Tejasvi, Trilokraj;
- Yang, Jingjing;
- Chandran, Vinod;
- Das, Sayantan;
- Callis-Duffin, Kristina;
- Ellinghaus, Eva;
- Enerbäck, Charlotta;
- Esko, Tõnu;
- Franke, Andre;
- Kang, Hyun M.;
- Krueger, Gerald G.;
- Lim, Henry W.;
- Rahman, Proton;
- Rosen, Cheryl F.;
- Weidinger, Stephan;
- Weichenthal, Michael
Publication type:
Article
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.
Published in:
2016
By:
- Prins, Bram. P.;
- Abbasi, Ali;
- Wong, Anson;
- Vaez, Ahmad;
- Nolte, Ilja;
- Franceschini, Nora;
- Stuart, Philip E.;
- Guterriez Achury, Javier;
- Mistry, Vanisha;
- Bradfield, Jonathan P.;
- Valdes, Ana M.;
- Bras, Jose;
- Shatunov, Aleksey;
- null, null;
- Lu, Chen;
- Han, Buhm;
- Raychaudhuri, Soumya;
- Bevan, Steve;
- Mayes, Maureen D.;
- Tsoi, Lam C.
Publication type:
journal article

Found: 29