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- Title
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
- Authors
Reilly, Svetlana N.; Xing Liu; Carnicer, Ricardo; Recalde, Alice; Muszkiewicz, Anna; Jayaram, Raja; Carena, Maria Cristina; Wijesurendra, Rohan; Stefanini, Matilde; Surdo, Nicoletta C.; Lomas, Oliver; Ratnatunga, Chandana; Sayeed, Rana; Krasopoulos, George; Rajakumar, Timothy; Bueno-Orovio, Alfonso; Verheule, Sander; Fulga, Tudor A.; Rodriguez, Blanca; Schotten, Ulrich
- Abstract
The article discusses the public health burden of atrial fibrillation (AF) due to its impact on the risk of stroke and heart failure. It examines the contribution of the lack of access to medical care and drugs to the poor health outcomes. It also cites the risk of arrhythmic death in patient who have experienced myocardial infarction.
- Subjects
ATRIAL fibrillation risk factors; HEART failure; HEALTH services accessibility; PATIENT acceptance of health care; HEALTH outcome assessment
- Publication
Science Translational Medicine, 2016, Vol 8, Issue 340, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aac4296