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- Title
A Novel, One-Step Palladium and Phenylsilane Activated Amidation from Allyl Ester on Solid Support.
- Authors
Zheming Ruan; Van Kirk, Katy; Cooper, Christopher B.; Lawrence, R. Michael
- Abstract
The direct conversion of solid-supported carboxylic acid allyl esters to carboxamides through the use of phenylsilane and catalytic Pd(PPh3)4 under mild reaction conditions is reported. The use of this methodology for the generation of a 48 compound solidphase array is described herein.
- Subjects
CATALYSIS; CARBOXYLIC acids; ORGANIC acids; PALLADIUM compounds; ESTERS; ORGANIC compounds; ORGANIC solvents; ACIDS
- Publication
Research Letters in Organic Chemistry, 2008, p1
- ISSN
1687-6865
- Publication type
Article
- DOI
10.1155/2008/696090