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- Title
HIV-Related Malignant Lymphoma: A Report of 46 Cases Observed in Italy.
- Authors
Tirelli, U.; Vaccher, E.; Ambrosini, A.; Andriani, A.; Silvestroni, Bianco; Broccia, G.; Chisesi, T.; Dessalvi, P.; Gobbi, M.; Fassio, F.; Deliliers, Lambertenghi; Lanza, F.; Lazzarin, A.; Lombardi, F.; Luzi, G.; Malleo, C.; Parrinello, E.A.; Proto, R.; Puppo, F.; Rezza, G.
- Abstract
We report 36 patients with non-Hodgkin's lymphomas (NHL) and 10 patients with Hodgkin's disease (HD), predominantly intravenous drug abusers (IVDA; 35 patients), diagnosed in 16 different Italian centers. The group of NHL has a median age of 26 years (range 16-64): 26 were IVDA, 3 polytransfused, 3 IVDA and homosexual men, 2 homosexual men and 2 without apparent risk for AIDS but carrying HIV antibodies. 81% of the evaluable patients had high-grade NHL (32% Burkitt's type) according to the Working Formulation, 15% intermediate and 4% low-grade. Out of 23 patients with stage reported, 16 (70%) were stage IV, 2 (9%) stage III, 1 (4%) stage II and 4 (17%) stage I (CNS involvement). The group with HD has a median age of 25 years (range 20-40), 9 were IVDA and 1 IVDA and homosexual. Of the 7 patients with subtype reported, 4 patients had nodular sclerosis and 3 mixed cellularity subtype. Stage III and IV were reported in 66% of the patients. The median survival is 4 months for NHL and 10 months for HD. The most common cause of death is opportunistic infection in 86% of the evaluable cases. Copyright © 1988 S. Karger AG, Basel
- Publication
Acta Haematologica, 1988, Vol 80, Issue 1, p49
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000205597