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- Title
The protective effect of stevia extract on the gastric mucosa of rainbow troutOncorhynchus mykiss(Walbaum) fed dietary histamine.
- Authors
Shiozaki, Kazuhiro; Nakano, Toshiki; Yamaguchi, Toshiyasu; Sato, Minoru; Sato, Naohiko
- Abstract
Stevia extract was made from stevia stem by extraction with boiling water and fermentation. The protective effect of a Stevia extract on rainbow trout (average weight, 12 g) fed 1% of dietary histamine for 4 weeks was investigated. Administration of dietary histamine to trout did not result in a reduction in growth rate or feed consumption but caused a gastric abnormality, e.g. exfoliation of the mucosal epithelium and atrophy of mucosal lamina propria. Stevia extract protected gastric tissue from histamine-induced damage. Pepsin activity in gastric fluid increased and liverα-tocopherol content was reduced after histamine treatment, but Stevia treatment prevented these abnormalities. The results suggest that the stevia extract might protect the rainbow trout stomach from histamine toxicity.
- Subjects
HISTAMINE; BIOGENIC amines; STEVIA; ASTERACEAE; CAMPANULALES; PEPSIN; ASPARTIC proteinases
- Publication
Aquaculture Research, 2004, Vol 35, Issue 15, p1421
- ISSN
1355-557X
- Publication type
Article
- DOI
10.1111/j.1365-2109.2004.01164.x