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- Title
Do vegetarians less frequently carry ESBL/pAmpC-producing Escherichia coli/Klebsiella pneumoniae compared with non-vegetarians?
- Authors
Meijs, Anouk P; Gijsbers, Esther F; Hengeveld, Paul D; Veenman, Christiaan; Roon, Annika M van; Hoek, Angela H A M van; Greeff, Sabine C de; Duijkeren, Engeline van; Dierikx, Cindy M; van Roon, Annika M; van Hoek, Angela H A M; de Greeff, Sabine C; van Duijkeren, Engeline
- Abstract
<bold>Background: </bold>ESBL and plasmid-mediated AmpC (pAmpC)-producing Enterobacteriaceae are frequently found on meat products in Dutch retail, especially on poultry.<bold>Objectives: </bold>We investigated whether vegetarians are at lower risk of carrying ESBL/pAmpC-producing Escherichia coli/Klebsiella pneumoniae (ESBL-E/K) compared with persons who consume meat.<bold>Methods: </bold>Vegetarians, pescatarians (vegetarians who eat fish) and non-vegetarians (persons who eat meat at least three times per week) were asked to send in a faecal sample and a questionnaire. ESBL-E/K were cultured and MLSTs were determined. ESBL/pAmpC genes were analysed using PCR and sequencing. The risk of ESBL-E/K carriage in the three study groups was analysed using multivariable logistic regression.<bold>Results: </bold>Prevalence of ESBL-E/K carriage was 8.0% in vegetarians (63/785; 95% CI 6.3-10.1), 6.9% in pescatarians (27/392; 95% CI 4.8-9.8) and 3.8% in non-vegetarians (14/365; 95% CI 2.3-6.3). Multivariable analysis showed an OR for ESBL-E/K carriage of 2.2 for vegetarians (95% CI 1.2-4.0) and 1.6 for pescatarians (95% CI 0.8-3.2) compared with non-vegetarians. The predominant MLST was E. coli ST131 and the most common ESBL genes were blaCTX-M-15, blaCTX-M-27, blaCTX-M-14 and blaCTX-M-1 in all diet groups. Independent risk factors for ESBL-E/K carriage were travel to Africa/Latin America/Asia (OR 4.6; 95% CI 2.8-7.7) in the past 6 months and rarely/never washing hands before food preparation (OR 2.5; 95% CI 1.2-5.0).<bold>Conclusions: </bold>Vegetarians and pescatarians did not have a lower risk of ESBL-E/K carriage compared with non-vegetarians, indicating that eating meat is not an important risk factor for ESBL-E/K carriage.
- Subjects
LATIN America; AFRICA; ASIA; VEGETARIAN foods; KLEBSIELLA pneumoniae; ESCHERICHIA coli; ENTEROBACTERIACEAE; VEGETARIANS; HAND washing; MEAT; KLEBSIELLA; BACTERIAL proteins; RESEARCH; SEQUENCE analysis; ANIMAL experimentation; RESEARCH methodology; MEDICAL cooperation; EVALUATION research; HYDROLASES; COMPARATIVE studies; ESCHERICHIA coli diseases; GENES; ANTIBIOTICS
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2020, Vol 75, Issue 3, p550
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/dkz483