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- Title
Modular 3D Printed Compressed Air Driven Continuous‐Flow Systems for Chemical Synthesis.
- Authors
Penny, Matthew R.; Rao, Zenobia X.; Peniche, Bruno Felício; Hilton, Stephen T.
- Abstract
In this present study, we describe the development of a low‐cost, small‐footprint and modular 3D printed continuous‐flow system that readily attaches to existing stirrer hotplates. Flow‐rates are controlled by compressed air that is typically present in all fume hoods, making it suitable for use by synthetic chemists. The length of the flow‐path and reaction residence time is regulated by control of the air‐flow and pressure and by addition of one or more 3D printed polypropylene (PP) circular disk reactors that were designed to fit a DrySyn Multi‐E base, which is found in most synthetic laboratories. The ease of use of the system, the facile control of flow‐rates and the solvent resistance of the PP reactors was demonstrated in a range of SNAr reactions to produce substituted ether derivatives highlighting the utility and modularity of the system.
- Subjects
CHEMICAL systems; COMPRESSED air; CHEMICAL synthesis; MODULAR construction; FUME hoods; ETHER derivatives; LABORATORIES
- Publication
European Journal of Organic Chemistry, 2019, Vol 2019, Issue 23, p3783
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201900423