We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
The Role of Hematological Parameters in Children with COVID-19, MIS-C, and Other Viral Infections.
- Authors
Arslan, Sema Yıldırım; Bal, Zümrüt Şahbudak; Özenen, Gizem Güner; Bilen, Nimet Melis; Özkaya, Pınar Yazıcı; Özkınay, Ferda; Karapınar, Bülent; Çiçek, Candan; Kurugöl, Zafer
- Abstract
Objective: It is known that coronavirus disease-2019 (COVID-19) showed a clinical course with milder symptoms in children than in adults. However, a multisystem inflammatory syndrome in children (MIS-C), which developed 2-4 weeks after COVID-19 infection, emerged in April 2021. Other respiratory viruses such as influenza, respiratory syncytial virus, and parainfluenza spread worldwide after loosening pandemic restrictions. Pediatricians were challenged to distinguish COVID-19, MIS-C, and other viral infections from each other. Herein, we have aimed to determine basic, simple hematological parameters that can predict the prognosis and outcomes of the patients with COVID-19 and MIS-C. Method: In this study, 300 pediatric inpatients including those with MIS-C, COVID-19, and other respiratory virus infections admitted to Ege University Faculty of Medicine between January 2018 and September 2021, were retrospectively evaluated. Results: The neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-monocyte ratio (NMR), derived NLR, and the systemic inflammatory index were higher in the MIS-C patients compared to others. The lymphocyte-to-monocyte ratio (LMR) and platelet-to-lymphocyte ratio (PLR) were lower in children with COVID-19 disease than those with MIS-C (p<0.05). Conclusions: In this study, we have shown that commonly used hematological tests, especially higher values of NLR, NMR for children with MIS-C, and lower levels of LMR for children with COVID-19, are significant and can help to determine the possible disease course of children at an early stage.
- Subjects
MULTISYSTEM inflammatory syndrome in children; VIRUS diseases; CORONAVIRUS diseases; COVID-19; MONOCYTE lymphocyte ratio; PLATELET lymphocyte ratio
- Publication
Journal of Behcet Uz Children's Hospital, 2023, Vol 13, Issue 3, p160
- ISSN
2822-4469
- Publication type
Article
- DOI
10.4274/jbuch.galenos.2023.21703